Tiocijanska kiselina

Tiocijanska kiselina
Skeletal formula of thiocyanic acid	Skeletal formula of thiocyanic acid with the explicit hydrogen added
	Nitridosulfanidougljenik
Identifikacija
CAS registarski broj	463-56-9
PubChem	781
ChemSpider	760
EINECS broj	207-337-4
KEGG	C01755
MeSH	thiocyanic+acid
ChEBI	29200
ChEMBL	CHEMBL84336
Gmelin Referenca	25178
3DMet	B00344
Jmol-3D slike	Slika 1
SMILES
	SC#N
InChI
	InChI=1S/CHNS/c2-1-3/h3H ; Kod: ZMZDMBWJUHKJPS-UHFFFAOYSA-N
Svojstva
Molekulska formula	CHNS
Molarna masa	59.09 g mol−1
Rastvorljivost u vodi	Meša se
log P	0,429
pKa	0,926
Baznost (pKb)	13,071
Opasnost
EU-klasifikacija	Xn
EU-indeks	615-003-00-8
R-oznake	R20/21/22, R32, R52/53
S-oznake	S2, S13
Srodna jedinjenja
Srodna alkannitrili	Vodonik cijanid; Cijanogen jodid; Cijanogen bromid; Cijanogen hlorid; Cijanogen fluorid; Acetonitril; Aminoacetonitril; Glikolonitril; Cijanogen;
	(šta je ovo?) (verifikuj) ; Ukoliko nije drugačije napomenuto, podaci se odnose na standardno stanje (25 °C, 100 kPa) materijala
	Infobox references

Tiocijanska kiselna je hemijsko jedinjenje sa formulom HSCN, koje postoji kao smeša sa izomernim jedinjenjem izotiocijanskom kiselinom (HNCS).^[8] Ona je sumporni analog cijanske kiseline (HOCN).

Ona je umereno slaba kiselina, sa pKa od 1,1 na 20 °C i ekstrapolisanom jonskom jačinom od nula.^[9]

Smatra se da HSCN ima trostruku vezu između ugljenika i azota. Ona je primećena spektroskopskim putem ali nije bila izolovana kao čista supstanca.^[10]

Reference uredi

↑ Merck Index, 11th Edition, 9257.
↑ „thiocyanic acid (CHEBI:29200)”. Chemical Entities of Biological Interest. USA: European Bioinformatics Institute. 18. 10. 2009.. Main.. Pristupljeno 5. 6. 2012.
↑ Li Q, Cheng T, Wang Y, Bryant SH (2010). „PubChem as a public resource for drug discovery.”. Drug Discov Today 15 (23-24): 1052-7. DOI:10.1016/j.drudis.2010.10.003. PMID 20970519. edit
↑ Evan E. Bolton, Yanli Wang, Paul A. Thiessen, Stephen H. Bryant (2008). „Chapter 12 PubChem: Integrated Platform of Small Molecules and Biological Activities”. Annual Reports in Computational Chemistry 4: 217-241. DOI:10.1016/S1574-1400(08)00012-1.
↑ Hettne KM, Williams AJ, van Mulligen EM, Kleinjans J, Tkachenko V, Kors JA. (2010). „Automatic vs. manual curation of a multi-source chemical dictionary: the impact on text mining”. J Cheminform 2 (1): 3. DOI:10.1186/1758-2946-2-3. PMID 20331846. edit
↑ Joanne Wixon, Douglas Kell (2000). „Website Review: The Kyoto Encyclopedia of Genes and Genomes — KEGG”. Yeast 17 (1): 48–55. DOI:10.1002/(SICI)1097-0061(200004)17:1<48::AID-YEA2>3.0.CO;2-H.
↑ Gaulton A, Bellis LJ, Bento AP, Chambers J, Davies M, Hersey A, Light Y, McGlinchey S, Michalovich D, Al-Lazikani B, Overington JP. (2012). „ChEMBL: a large-scale bioactivity database for drug discovery”. Nucleic Acids Res 40 (Database issue): D1100-7. DOI:10.1093/nar/gkr777. PMID 21948594. edit
↑ Holleman, A. F.; Wiberg, E. Inorganic Chemistry Academic Press: San Diego, 2001. ISBN 0-12-352651-5.
↑ Martell, A. E.; Smith, R. M.; Motelaitis, R. J. NIST Database 46 National Institute of Standards and Technology: Gaithersburg, MD, 2001.
↑ Wierzejewska, M.; Mielke, Z. (2001). „Photolysis of Isothiocyanic Acid HNCS in Low-Temperature Matrices. Infrared Detection of HSCN and HSNC Isomers”. Chemical Physics Letters 349: 227–234. DOI:10.1016/S0009-2614(01)01180-0.

Spoljašnje veze uredi

Portal Hemija

[1] Merck Index, 11th Edition, 9257.

[2] „thiocyanic acid (CHEBI:29200)”. Chemical Entities of Biological Interest. USA: European Bioinformatics Institute. 18. 10. 2009.. Main.. Pristupljeno 5. 6. 2012.

[3] Li Q, Cheng T, Wang Y, Bryant SH (2010). „PubChem as a public resource for drug discovery.”. Drug Discov Today 15 (23-24): 1052-7. DOI:10.1016/j.drudis.2010.10.003. PMID 20970519. edit

[4] Evan E. Bolton, Yanli Wang, Paul A. Thiessen, Stephen H. Bryant (2008). „Chapter 12 PubChem: Integrated Platform of Small Molecules and Biological Activities”. Annual Reports in Computational Chemistry 4: 217-241. DOI:10.1016/S1574-1400(08)00012-1.

[5] Hettne KM, Williams AJ, van Mulligen EM, Kleinjans J, Tkachenko V, Kors JA. (2010). „Automatic vs. manual curation of a multi-source chemical dictionary: the impact on text mining”. J Cheminform 2 (1): 3. DOI:10.1186/1758-2946-2-3. PMID 20331846. edit

[6] Joanne Wixon, Douglas Kell (2000). „Website Review: The Kyoto Encyclopedia of Genes and Genomes — KEGG”. Yeast 17 (1): 48–55. DOI:10.1002/(SICI)1097-0061(200004)17:1<48::AID-YEA2>3.0.CO;2-H.

[7] Gaulton A, Bellis LJ, Bento AP, Chambers J, Davies M, Hersey A, Light Y, McGlinchey S, Michalovich D, Al-Lazikani B, Overington JP. (2012). „ChEMBL: a large-scale bioactivity database for drug discovery”. Nucleic Acids Res 40 (Database issue): D1100-7. DOI:10.1093/nar/gkr777. PMID 21948594. edit

[8] Holleman, A. F.; Wiberg, E. Inorganic Chemistry Academic Press: San Diego, 2001. ISBN 0-12-352651-5.

[9] Martell, A. E.; Smith, R. M.; Motelaitis, R. J. NIST Database 46 National Institute of Standards and Technology: Gaithersburg, MD, 2001.

[10] Wierzejewska, M.; Mielke, Z. (2001). „Photolysis of Isothiocyanic Acid HNCS in Low-Temperature Matrices. Infrared Detection of HSCN and HSNC Isomers”. Chemical Physics Letters 349: 227–234. DOI:10.1016/S0009-2614(01)01180-0.

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