Timidin fosforilaza
Timidin fosforilaza (EC 2.4.2.4, pirimidinska fosforilaza, timidin-ortofosfatna dezoksiriboziltransferaza, regulatori životinjskog rasta, endotelni faktori ćelijskog rasta izvedeni iz krvnih trombocita, endotelni faktori ćelijskog rasta izvedeni iz krvnih trombocita, dezoksitimidinska fosforilaza, gliostatini, pirimidin dezoksinukleozidna fosforilaza, timidin:fosfat dezoksi-D-riboziltransferaza) je enzim sa sistematskim imenom timidin:fosfat dezoksi-alfa-D-riboziltransferaza.[1][2][3] Ovaj enzim katalizuje sledeću hemijsku reakciju
Timidin fosforilaza | |||||||||
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Identifikatori | |||||||||
EC broj | 2.4.2.4 | ||||||||
CAS broj | 9030-23-3 | ||||||||
IntEnz | IntEnz view | ||||||||
BRENDA | BRENDA entry | ||||||||
ExPASy | NiceZyme view | ||||||||
KEGG | KEGG entry | ||||||||
MetaCyc | metabolic pathway | ||||||||
PRIAM | profile | ||||||||
PDB | RCSB PDB PDBe PDBj PDBsum | ||||||||
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Enzim u pojedinim tkivima takođe katalizuje reakcije dezoksiriboziltransferaze.
Reference uredi
- ↑ Friedkin, M. and Roberts, D. (1954). „The enzymatic synthesis of nucleosides. I. Thymidine phosphorylase in mammalian tissue”. J. Biol. Chem. 207: 245-256. PMID 13152099.
- ↑ Zimmerman, M. and Seidenberg, J. (1964). „Deoxyribosyl transfer. I. Thymidine phosphorylase and nucleoside deoxyribosyltransferase in normal and malignant tissues”. J. Biol. Chem. 239: 2618-2621. PMID 14235544.
- ↑ Zimmerman, M. (1964). „Deoxyribosyl transfer. II. Nucleoside:pyrimidine deoxyribosyltransferase activity of three partially purified thymidine phosphorylases”. J. Biol. Chem. 239: 2622-2627. PMID 14235545.
Literatura uredi
- Nicholas C. Price, Lewis Stevens (1999). Fundamentals of Enzymology: The Cell and Molecular Biology of Catalytic Proteins (Third izd.). USA: Oxford University Press. ISBN 019850229X.
- Eric J. Toone (2006). Advances in Enzymology and Related Areas of Molecular Biology, Protein Evolution (Volume 75 izd.). Wiley-Interscience. ISBN 0471205036.
- Branden C, Tooze J.. Introduction to Protein Structure. New York, NY: Garland Publishing. ISBN: 0-8153-2305-0.
- Irwin H. Segel. Enzyme Kinetics: Behavior and Analysis of Rapid Equilibrium and Steady-State Enzyme Systems (Book 44 izd.). Wiley Classics Library. ISBN 0471303097.
- Robert A. Copeland (2013). Evaluation of Enzyme Inhibitors in Drug Discovery: A Guide for Medicinal Chemists and Pharmacologists (2nd izd.). Wiley-Interscience. ISBN 111848813X.
- Gerhard Michal, Dietmar Schomburg (2012). Biochemical Pathways: An Atlas of Biochemistry and Molecular Biology (2nd izd.). Wiley. ISBN 0470146842.