Sve-trans-8'-apo-beta-karotenal 15,15'-oksigenaza
Sve-trans-8'-apo-beta-karotenal 15,15'-oksigenaza (EC 1.14.99.41, Diox1, ACO, 8'-apo-beta-karotenal 15,15'-oksigenaza) je enzim sa sistematskim imenom sve-trans-8'-apo-beta-karotenal:kiseonik 15,15'-oksidoreduktaza (razgradnja veze).[1][2] Ovaj enzim katalizuje sledeću hemijsku reakciju
Sve-trans-8'-apo-beta-karotenal 15,15'-oksigenaza | |||||||||
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Identifikatori | |||||||||
EC broj | 1.14.99.41 | ||||||||
IntEnz | IntEnz view | ||||||||
BRENDA | BRENDA entry | ||||||||
ExPASy | NiceZyme view | ||||||||
KEGG | KEGG entry | ||||||||
MetaCyc | metabolic pathway | ||||||||
PRIAM | profile | ||||||||
PDB | RCSB PDB PDBe PDBj PDBsum | ||||||||
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- sve-trans-8'-apo-beta-karotenal + O2 sve-trans-retinal + (2E,4E,6E)-2,6-dimetilokta-2,4,6-trienedial
Ovaj enzim sadrži Fe2+-4His strukturu. On učestvuje u retinalnoj biosintezi kod bakterija.
Reference uredi
- ↑ Ruch, S., Beyer, P., Ernst, H. and Al-Babili, S. (2005). „Retinal biosynthesis in Eubacteria: in vitro characterization of a novel carotenoid oxygenase from Synechocystis sp. PCC 6803”. Mol. Microbiol. 55: 1015-1024. PMID 15686550.
- ↑ Kloer, D.P., Ruch, S., Al-Babili, S., Beyer, P. and Schulz, G.E. (2005). „The structure of a retinal-forming carotenoid oxygenase”. Science 308: 267-269. PMID 15821095.
Literatura uredi
- Nicholas C. Price, Lewis Stevens (1999). Fundamentals of Enzymology: The Cell and Molecular Biology of Catalytic Proteins (Third izd.). USA: Oxford University Press. ISBN 019850229X.
- Eric J. Toone (2006). Advances in Enzymology and Related Areas of Molecular Biology, Protein Evolution (Volume 75 izd.). Wiley-Interscience. ISBN 0471205036.
- Branden C, Tooze J.. Introduction to Protein Structure. New York, NY: Garland Publishing. ISBN: 0-8153-2305-0.
- Irwin H. Segel. Enzyme Kinetics: Behavior and Analysis of Rapid Equilibrium and Steady-State Enzyme Systems (Book 44 izd.). Wiley Classics Library. ISBN 0471303097.
- Robert A. Copeland (2013). Evaluation of Enzyme Inhibitors in Drug Discovery: A Guide for Medicinal Chemists and Pharmacologists (2nd izd.). Wiley-Interscience. ISBN 111848813X.
- Gerhard Michal, Dietmar Schomburg (2012). Biochemical Pathways: An Atlas of Biochemistry and Molecular Biology (2nd izd.). Wiley. ISBN 0470146842.