Striktozidinska beta-glukozidaza
Striktozidinska beta-glukozidaza (EC 3.2.1.105, 3alpha(S)-strictosidine beta-glucosidase) je enzim sa sistematskim imenom striktozidin beta-D-glukohidrolaza.[1][2] Ovaj enzim katalizuje sledeću hemijsku reakciju
| Striktozidinska beta-glukozidaza | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| Identifikatori | |||||||||
| EC broj | 3.2.1.105 | ||||||||
| CAS broj | 73379-57-4 | ||||||||
| IntEnz | IntEnz view | ||||||||
| BRENDA | BRENDA entry | ||||||||
| ExPASy | NiceZyme view | ||||||||
| KEGG | KEGG entry | ||||||||
| MetaCyc | metabolic pathway | ||||||||
| PRIAM | profile | ||||||||
| PDB | RCSB PDB PDBe PDBj PDBsum | ||||||||
| |||||||||
- striktozidin + H2O D-glukoza + striktozidin aglikon
Ovaj enzim ne deluje na brojne blisko srodne glikozide.
Reference uredi
- ↑ Hemscheidt, T. and Zenk, M.H. (1980). „Glucosidases involved in indole alkaloid biosynthesis of Catharanthus cell cultures”. FEBS Lett. 110: 187-191. PMID 6768587.
- ↑ Barleben, L., Ma, X., Koepke, J., Peng, G., Michel, H. and Stöckigt, J. (2005). „Expression, purification, crystallization and preliminary X-ray analysis of strictosidine glucosidase, an enzyme initiating biosynthetic pathways to a unique diversity of indole alkaloid skeletons”. Biochim. Biophys. Acta 1747: 89-92. PMID 15680242.
Literatura uredi
- Nicholas C. Price, Lewis Stevens (1999). Fundamentals of Enzymology: The Cell and Molecular Biology of Catalytic Proteins (Third izd.). USA: Oxford University Press. ISBN 019850229X.
- Eric J. Toone (2006). Advances in Enzymology and Related Areas of Molecular Biology, Protein Evolution (Volume 75 izd.). Wiley-Interscience. ISBN 0471205036.
- Branden C, Tooze J.. Introduction to Protein Structure. New York, NY: Garland Publishing. ISBN: 0-8153-2305-0.
- Irwin H. Segel. Enzyme Kinetics: Behavior and Analysis of Rapid Equilibrium and Steady-State Enzyme Systems (Book 44 izd.). Wiley Classics Library. ISBN 0471303097.
- Robert A. Copeland (2013). Evaluation of Enzyme Inhibitors in Drug Discovery: A Guide for Medicinal Chemists and Pharmacologists (2nd izd.). Wiley-Interscience. ISBN 111848813X.
- Gerhard Michal, Dietmar Schomburg (2012). Biochemical Pathways: An Atlas of Biochemistry and Molecular Biology (2nd izd.). Wiley. ISBN 0470146842.