Streptogrizin A
Streptogrizin A (EC 3.4.21.80, Streptomyces griseus proteaza A, proteaza A, proteinaza A, Streptomyces griseus proteinaza A, Streptomyces griseus serinska proteinaza 3, Streptomyces griseus serinska proteinaza A) je enzim.[1][2][3][4][5] Ovaj enzim katalizuje sledeću hemijsku reakciju
| Streptogrizin A | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| Identifikatori | |||||||||
| EC broj | 3.4.21.80 | ||||||||
| CAS broj | 55326-50-6 | ||||||||
| IntEnz | IntEnz view | ||||||||
| BRENDA | BRENDA entry | ||||||||
| ExPASy | NiceZyme view | ||||||||
| KEGG | KEGG entry | ||||||||
| MetaCyc | metabolic pathway | ||||||||
| PRIAM | profile | ||||||||
| PDB | RCSB PDB PDBe PDBj PDBsum | ||||||||
| |||||||||
- Hidroliza proteina sa specifičnošću koja je slična himotripsinu
Ovaj enzim je izolovan iz bakterije Streptomyces griseus.
Reference uredi
- ↑ Johnson, P. and Smillie, L.B. (1971). „The disulfide bridge sequences of a serine protease of wide specificity from Streptomyces griseus”. Can. J. Biochem. 49: 548-562. PMID 5575653.
- ↑ Sielecki, A.R., Hendrickson, W.A., Broughton, C.G., Delbaere, L.T.J., Brayer, G.D. and James, M.N.G. (1979). „Protein structure refinement: Streptomyces griseus serine protease A at 1.8 Å resolution”. J. Mol. Biol. 134: 781-804. PMID 119870.
- ↑ James, M.N.G., Sielecki, A.R., Brayer, G.D., Delbaere, L.T.J. and Bauer, C.-A. (1980). „Structures of product and inhibitor complexes of Streptomyces griseus protease A at 1.8 Å resolution”. J. Mol. Biol. 144: 43-88. PMID 6783761.
- ↑ Delbaere, L.T.J. and Brayer, G.D. (1985). „The 1.8 Å structure of the complex between chymostatin and Streptomyces griseus protease A. A model for serine protease catalytic tetrahedral intermediates”. J. Mol. Biol. 183: 89-103. PMID 3892018.
- ↑ Henderson, G., Krygsman, P., Liu, C.J., Davey, C.C. and Malek, L.T. (1987). „Characterization and structure of genes for proteases A and B from Streptomyces griseus”. J. Bacteriol. 169: 3778-3784. PMID 3112129.
Literatura uredi
- Nicholas C. Price, Lewis Stevens (1999). Fundamentals of Enzymology: The Cell and Molecular Biology of Catalytic Proteins (Third izd.). USA: Oxford University Press. ISBN 019850229X.
- Eric J. Toone (2006). Advances in Enzymology and Related Areas of Molecular Biology, Protein Evolution (Volume 75 izd.). Wiley-Interscience. ISBN 0471205036.
- Branden C, Tooze J.. Introduction to Protein Structure. New York, NY: Garland Publishing. ISBN: 0-8153-2305-0.
- Irwin H. Segel. Enzyme Kinetics: Behavior and Analysis of Rapid Equilibrium and Steady-State Enzyme Systems (Book 44 izd.). Wiley Classics Library. ISBN 0471303097.
- Robert A. Copeland (2013). Evaluation of Enzyme Inhibitors in Drug Discovery: A Guide for Medicinal Chemists and Pharmacologists (2nd izd.). Wiley-Interscience. ISBN 111848813X.
- Gerhard Michal, Dietmar Schomburg (2012). Biochemical Pathways: An Atlas of Biochemistry and Molecular Biology (2nd izd.). Wiley. ISBN 0470146842.