Saharoza fosforilaza
Saharoza fosforilaza (EC 2.4.1.7, saharozna glukoziltransferaza, disaharidna glukoziltransferaza) je enzim sa sistematskim imenom saharoza:fosfat alfa-D-glukoziltransferaza.[1][2][3] Ovaj enzim katalizuje sledeću hemijsku reakciju
| Saharoza fosforilaza | |||||||||
|---|---|---|---|---|---|---|---|---|---|
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| Saharoza fosforilaza homodimer, Bifidobacterium adolescentis | |||||||||
| Identifikatori | |||||||||
| EC broj | 2.4.1.7 | ||||||||
| CAS broj | 9074-06-0 | ||||||||
| IntEnz | IntEnz view | ||||||||
| BRENDA | BRENDA entry | ||||||||
| ExPASy | NiceZyme view | ||||||||
| KEGG | KEGG entry | ||||||||
| MetaCyc | metabolic pathway | ||||||||
| PRIAM | profile | ||||||||
| PDB | RCSB PDB PDBe PDBj PDBsum | ||||||||
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U direktnoj reakciji, arsenat može da zameni fosfat. U reverznoj reakciji, razne ketoze i L-arabinoza mogu da zamene D-fruktozu.
Reference uredi
- ↑ Doudoroff, M. (1961). „Disaccharide phosphorylases”. u: Boyer, P.D., Lardy, H. and Myrbäck, K.. The Enzymes. 5 (2nd izd.). New York: Academic Press. str. 229-236.
- ↑ Hassid, W.Z. and Doudoroff, M. (1950). „Enzymic synthesis of sucrose and other disaccharides”. Adv. Carbohydr. Chem. 5: 29-48. PMID 14783033.
- ↑ Silverstein, R., Voet, J., Reed, D. and Abeles, R.H. (1967). „Purification and mechanism of action of sucrose phosphorylase”. J. Biol. Chem. 242: 1338-1346. PMID 4381552.
Literatura uredi
- Nicholas C. Price, Lewis Stevens (1999). Fundamentals of Enzymology: The Cell and Molecular Biology of Catalytic Proteins (Third izd.). USA: Oxford University Press. ISBN 019850229X.
- Eric J. Toone (2006). Advances in Enzymology and Related Areas of Molecular Biology, Protein Evolution (Volume 75 izd.). Wiley-Interscience. ISBN 0471205036.
- Branden C, Tooze J.. Introduction to Protein Structure. New York, NY: Garland Publishing. ISBN: 0-8153-2305-0.
- Irwin H. Segel. Enzyme Kinetics: Behavior and Analysis of Rapid Equilibrium and Steady-State Enzyme Systems (Book 44 izd.). Wiley Classics Library. ISBN 0471303097.
- Robert A. Copeland (2013). Evaluation of Enzyme Inhibitors in Drug Discovery: A Guide for Medicinal Chemists and Pharmacologists (2nd izd.). Wiley-Interscience. ISBN 111848813X.
- Gerhard Michal, Dietmar Schomburg (2012). Biochemical Pathways: An Atlas of Biochemistry and Molecular Biology (2nd izd.). Wiley. ISBN 0470146842.
- Doudoroff, M. (1961). „Disaccharide phosphorylases”. u: Boyer, P.D., Lardy, H. and Myrbäck, K.. The Enzymes. 5 (2nd izd.). New York: Academic Press. str. 229-236.