Ramnogalakturonanska ramnohidrolaza
Ramnogalakturonanska ramnohidrolaza (EC 3.2.1.174, RG-ramnohidrolaza, RG alfa-L-ramnopiranohidrolaza) je enzim sa sistematskim imenom ramnogalakturonan oligosaharid alfa-L-Rha-(1->4)-alfa-D-GalA ramnohidrolaza.[1][2] Ovaj enzim katalizuje sledeću hemijsku reakciju
| Ramnogalakturonanska ramnohidrolaza | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| Identifikatori | |||||||||
| EC broj | 3.2.1.174 | ||||||||
| IntEnz | IntEnz view | ||||||||
| BRENDA | BRENDA entry | ||||||||
| ExPASy | NiceZyme view | ||||||||
| KEGG | KEGG entry | ||||||||
| MetaCyc | metabolic pathway | ||||||||
| PRIAM | profile | ||||||||
| PDB | RCSB PDB PDBe PDBj PDBsum | ||||||||
| |||||||||
- eksohidroliza alfa-L-Rha-(1->4)-alfa-D-GalA veze u ramnogalakturonanskim oligosaharidima sa inicijalnom inverzijom konfiguracije čime se oslobađa beta-L-ramnoza sa neredukujućeg kraja ramnogalakturonanskih oligosaharida
Ovaj enzim učestvuje u degradaciji ramnogalakturonana I kod Aspergillus aculeatus.
Reference uredi
- ↑ Pitson, S.M., Mutter, M., van den Broek, L.A., Voragen, A.G. and Beldman, G. (1998). „Stereochemical course of hydrolysis catalysed by α-L-rhamnosyl and α-D-galacturonosyl hydrolases from Aspergillus aculeatus”. Biochem. Biophys. Res. Commun. 242: 552-559. PMID 9464254.
- ↑ Mutter, M., Beldman, G., Schols, H.A. and Voragen, A.G. (1994). „Rhamnogalacturonan α-L-rhamnopyranohydrolase. A novel enzyme specific for the terminal nonreducing rhamnosyl unit in rhamnogalacturonan regions of pectin”. Plant Physiol. 106: 241-250. PMID 7972516.
Literatura uredi
- Nicholas C. Price, Lewis Stevens (1999). Fundamentals of Enzymology: The Cell and Molecular Biology of Catalytic Proteins (Third izd.). USA: Oxford University Press. ISBN 019850229X.
- Eric J. Toone (2006). Advances in Enzymology and Related Areas of Molecular Biology, Protein Evolution (Volume 75 izd.). Wiley-Interscience. ISBN 0471205036.
- Branden C, Tooze J.. Introduction to Protein Structure. New York, NY: Garland Publishing. ISBN: 0-8153-2305-0.
- Irwin H. Segel. Enzyme Kinetics: Behavior and Analysis of Rapid Equilibrium and Steady-State Enzyme Systems (Book 44 izd.). Wiley Classics Library. ISBN 0471303097.
- Robert A. Copeland (2013). Evaluation of Enzyme Inhibitors in Drug Discovery: A Guide for Medicinal Chemists and Pharmacologists (2nd izd.). Wiley-Interscience. ISBN 111848813X.
- Gerhard Michal, Dietmar Schomburg (2012). Biochemical Pathways: An Atlas of Biochemistry and Molecular Biology (2nd izd.). Wiley. ISBN 0470146842.