Nukleozid dezoksiriboziltransferaza
Nukleozid dezoksiriboziltransferaza (EC 2.4.2.6, purin (pirimidin) nukleozid:purin (pirimidin) dezoksiribozil transferaza, dezoksiriboza transferaza, nukleozid trans-N-dezoksiribozilaza, trans-dezoksiribozilaza, trans-N-dezoksiribozilaza, trans-N-glikosidaza, nukleozid dezoksiriboziltransferaza I (purin nukleozid:purin dezoksiriboziltransferaza: striktno specifična za transfer između purinskih baza), nukleozid dezoksiriboziltransferaza II (purin (pirimidin) nukleozid:purin (pirimidin) dezoksiriboziltransferaza)) je enzim sa sistematskim imenom nukleozid:purin (pirimidin) dezoksi-D-riboziltransferaza.[1][2][3] Ovaj enzim katalizuje sledeću hemijsku reakciju
| Nukleozid dezoksiriboziltransferaza | |||||||||
|---|---|---|---|---|---|---|---|---|---|
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| Nukleozid dezoksiriboziltransferaza homohexamer, Lactobacillus leichmannii | |||||||||
| Identifikatori | |||||||||
| EC broj | 2.4.2.6 | ||||||||
| CAS broj | 9026-86-2 | ||||||||
| IntEnz | IntEnz view | ||||||||
| BRENDA | BRENDA entry | ||||||||
| ExPASy | NiceZyme view | ||||||||
| KEGG | KEGG entry | ||||||||
| MetaCyc | metabolic pathway | ||||||||
| PRIAM | profile | ||||||||
| PDB | RCSB PDB PDBe PDBj PDBsum | ||||||||
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- 2-dezoksi-D-ribozil-baza1 + baza2 2-dezoksi-D-ribozil-baza2 + baza1
Baza 1 i baza 2 su razni purini i pirimidini.
Reference uredi
- ↑ Kalckar, H.M., MacNutt, W.S. and Hoff-Jørgensen, E. (1952). „Trans-N-glycosidase studied with radioactive adenine”. Biochem. J. 50: 397-400. PMID 14915963.
- ↑ MacNutt, W.S. (1952). „The enzymically catalysed transfer of the deoxyribosyl group from one purine or pyrimidine to another”. Biochem. J. 50: 384-397. PMID 14915962.
- ↑ Roush, A.H. and Betz, R.F. (1958). „Purification and properties of trans-N-deoxyribosylase”. J. Biol. Chem. 233: 261-266. PMID 13563482.
Literatura uredi
- Nicholas C. Price, Lewis Stevens (1999). Fundamentals of Enzymology: The Cell and Molecular Biology of Catalytic Proteins (Third izd.). USA: Oxford University Press. ISBN 019850229X.
- Eric J. Toone (2006). Advances in Enzymology and Related Areas of Molecular Biology, Protein Evolution (Volume 75 izd.). Wiley-Interscience. ISBN 0471205036.
- Branden C, Tooze J.. Introduction to Protein Structure. New York, NY: Garland Publishing. ISBN: 0-8153-2305-0.
- Irwin H. Segel. Enzyme Kinetics: Behavior and Analysis of Rapid Equilibrium and Steady-State Enzyme Systems (Book 44 izd.). Wiley Classics Library. ISBN 0471303097.
- Robert A. Copeland (2013). Evaluation of Enzyme Inhibitors in Drug Discovery: A Guide for Medicinal Chemists and Pharmacologists (2nd izd.). Wiley-Interscience. ISBN 111848813X.
- Gerhard Michal, Dietmar Schomburg (2012). Biochemical Pathways: An Atlas of Biochemistry and Molecular Biology (2nd izd.). Wiley. ISBN 0470146842.