Nikotinamidaza
Nikotinamidaza (EC 3.5.1.19, nikotinamidna deaminaza, nikotinamidna amidaza, YNDaza) je enzim sa sistematskim imenom nikotinamid amidohidrolaza.[1][2] Ovaj enzim katalizuje sledeću hemijsku reakciju
| Nikotinamidaza | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| Identifikatori | |||||||||
| EC broj | 3.5.1.19 | ||||||||
| CAS broj | 9033-32-3 | ||||||||
| IntEnz | IntEnz view | ||||||||
| BRENDA | BRENDA entry | ||||||||
| ExPASy | NiceZyme view | ||||||||
| KEGG | KEGG entry | ||||||||
| MetaCyc | metabolic pathway | ||||||||
| PRIAM | profile | ||||||||
| PDB | RCSB PDB PDBe PDBj PDBsum | ||||||||
| |||||||||
- nikotinamid + H2O nikotinat + NH3
Reference uredi
- ↑ Petrack, B., Greengard, P., Craston, A. and Sheppy, F. (1965). „Nicotinamide deamidase from mammalian liver”. J. Biol. Chem. 240: 1725-1730. PMID 14285515.
- ↑ Sarma, D.S.R., Rajalakshmi, S. and Sarma, S. (1964). „Studies on the enzymes involved in nicotinamide adenine dinucleotide metabolism in Aspergillus niger”. Biochim. Biophys. Acta 81: 311-322.
Literatura uredi
- Nicholas C. Price, Lewis Stevens (1999). Fundamentals of Enzymology: The Cell and Molecular Biology of Catalytic Proteins (Third izd.). USA: Oxford University Press. ISBN 019850229X.
- Eric J. Toone (2006). Advances in Enzymology and Related Areas of Molecular Biology, Protein Evolution (Volume 75 izd.). Wiley-Interscience. ISBN 0471205036.
- Branden C, Tooze J.. Introduction to Protein Structure. New York, NY: Garland Publishing. ISBN: 0-8153-2305-0.
- Irwin H. Segel. Enzyme Kinetics: Behavior and Analysis of Rapid Equilibrium and Steady-State Enzyme Systems (Book 44 izd.). Wiley Classics Library. ISBN 0471303097.
- Robert A. Copeland (2013). Evaluation of Enzyme Inhibitors in Drug Discovery: A Guide for Medicinal Chemists and Pharmacologists (2nd izd.). Wiley-Interscience. ISBN 111848813X.
- Gerhard Michal, Dietmar Schomburg (2012). Biochemical Pathways: An Atlas of Biochemistry and Molecular Biology (2nd izd.). Wiley. ISBN 0470146842.