Muginenska kiselina 3-dioksigenaza
Muginenska kiselina 3-dioksigenaza (EC 1.14.11.25, IDS2) je enzim sa sistematskim imenom muginenska kiselina,2-oksoglutarat:kiseonik oksidoreduktaza (3-hidroksilacija).[1][2] Ovaj enzim katalizuje sledeću hemijsku reakciju
| Muginenska kiselina 3-dioksigenaza | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| Identifikatori | |||||||||
| EC broj | 1.14.11.25 | ||||||||
| IntEnz | IntEnz view | ||||||||
| BRENDA | BRENDA entry | ||||||||
| ExPASy | NiceZyme view | ||||||||
| KEGG | KEGG entry | ||||||||
| MetaCyc | metabolic pathway | ||||||||
| PRIAM | profile | ||||||||
| PDB | RCSB PDB PDBe PDBj PDBsum | ||||||||
| |||||||||
- (1) mugineinska kiselina + 2-oksoglutarat + O2 3-epihidroksimugineinska kiselina + sukcinat + CO2
- (2) 2'-dezoksimugineinska kiselina + 2-oksoglutarat + O2 3-epihidroksi-2'-dezoksimugineinska kiselina + sukcinat + CO2
Za rad ovog enzima je neophodan Fe2+ jon.
Reference uredi
- ↑ Nakanishi, H., Yamaguchi, H., Sasakuma, T., Nishizawa, N.K. and Mori, S. (2000). „Two dioxygenase genes, Ids3 and Ids2, from Hordeum vulgare are involved in the biosynthesis of mugineic acid family phytosiderophores”. Plant Mol. Biol. 44: 199-207. PMID 11117263.
- ↑ Okumura, N., Nishizawa, N.K., Umehara, Y., Ohata, T., Nakanishi, H., Yamaguchi, T., Chino, M. and Mori. S. (1994). „A dioxygenase gene (Ids2) expressed under iron deficiency conditions in the roots of Hordeum vulgare”. Plant Mol. Biol. 25: 705-719. PMID 8061321.
Literatura uredi
- Nicholas C. Price, Lewis Stevens (1999). Fundamentals of Enzymology: The Cell and Molecular Biology of Catalytic Proteins (Third izd.). USA: Oxford University Press. ISBN 019850229X.
- Eric J. Toone (2006). Advances in Enzymology and Related Areas of Molecular Biology, Protein Evolution (Volume 75 izd.). Wiley-Interscience. ISBN 0471205036.
- Branden C, Tooze J.. Introduction to Protein Structure. New York, NY: Garland Publishing. ISBN: 0-8153-2305-0.
- Irwin H. Segel. Enzyme Kinetics: Behavior and Analysis of Rapid Equilibrium and Steady-State Enzyme Systems (Book 44 izd.). Wiley Classics Library. ISBN 0471303097.
- Robert A. Copeland (2013). Evaluation of Enzyme Inhibitors in Drug Discovery: A Guide for Medicinal Chemists and Pharmacologists (2nd izd.). Wiley-Interscience. ISBN 111848813X.
- Gerhard Michal, Dietmar Schomburg (2012). Biochemical Pathways: An Atlas of Biochemistry and Molecular Biology (2nd izd.). Wiley. ISBN 0470146842.