Metilizocitratna lijaza
(Preusmjereno sa stranice MICL)
Metilizocitratna lijaza (EC 4.1.3.30, 2-metilizocitratna lijaza, MICL, (2S,3R)-3-hidroksibutan-1,2,3-trikarboksilat piruvat-lijaza) je enzim sa sistematskim imenom (2S,3R)-3-hidroksibutan-1,2,3-trikarboksilat piruvat-lijaza (formira sukcinat).[1][2] Ovaj enzim katalizuje sledeću hemijsku reakciju
| Metilizocitratna lijaza | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| Identifikatori | |||||||||
| EC broj | 4.1.3.30 | ||||||||
| CAS broj | 57827-77-7 | ||||||||
| IntEnz | IntEnz view | ||||||||
| BRENDA | BRENDA entry | ||||||||
| ExPASy | NiceZyme view | ||||||||
| KEGG | KEGG entry | ||||||||
| MetaCyc | metabolic pathway | ||||||||
| PRIAM | profile | ||||||||
| PDB | RCSB PDB PDBe PDBj PDBsum | ||||||||
| |||||||||
Ovaj enzim deluje na treo-Ds-2-metilizocitrat.
Reference uredi
- ↑ Tabuchi, T. and Satoh, T. (1976). „Distinction between isocitrate lyase and methylisocitrate lyase in Candida lipolytica”. Agric. Biol. Chem. 40: 1863-1869.
- ↑ Tabuchi, T. and Satoh, T. (1977). „Purification and properties of methylisocitrate lyase, a key enzyme in propionate metabolism, from Candida lipolytica”. Agric. Biol. Chem. 41: 169-174.
Literatura uredi
- Nicholas C. Price, Lewis Stevens (1999). Fundamentals of Enzymology: The Cell and Molecular Biology of Catalytic Proteins (Third izd.). USA: Oxford University Press. ISBN 019850229X.
- Eric J. Toone (2006). Advances in Enzymology and Related Areas of Molecular Biology, Protein Evolution (Volume 75 izd.). Wiley-Interscience. ISBN 0471205036.
- Branden C, Tooze J.. Introduction to Protein Structure. New York, NY: Garland Publishing. ISBN: 0-8153-2305-0.
- Irwin H. Segel. Enzyme Kinetics: Behavior and Analysis of Rapid Equilibrium and Steady-State Enzyme Systems (Book 44 izd.). Wiley Classics Library. ISBN 0471303097.
- Robert A. Copeland (2013). Evaluation of Enzyme Inhibitors in Drug Discovery: A Guide for Medicinal Chemists and Pharmacologists (2nd izd.). Wiley-Interscience. ISBN 111848813X.
- Gerhard Michal, Dietmar Schomburg (2012). Biochemical Pathways: An Atlas of Biochemistry and Molecular Biology (2nd izd.). Wiley. ISBN 0470146842.