Lizin 2-monooksigenaza
Lizin 2-monooksigenaza (EC 1.13.12.2, lizinska oksigenaza, lizinska monooksigenaza, L-lizin-2-monooksigenaza) je enzim sa sistematskim imenom L-lizin:kiseonik 2-oksidoreduktaza (dekarboksilacija).[1][2][3] Ovaj enzim katalizuje sledeću hemijsku reakciju
| Lizin 2-monooksigenaza | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| Identifikatori | |||||||||
| EC broj | 1.13.12.2 | ||||||||
| CAS broj | 9031-22-5 | ||||||||
| IntEnz | IntEnz view | ||||||||
| BRENDA | BRENDA entry | ||||||||
| ExPASy | NiceZyme view | ||||||||
| KEGG | KEGG entry | ||||||||
| MetaCyc | metabolic pathway | ||||||||
| PRIAM | profile | ||||||||
| PDB | RCSB PDB PDBe PDBj PDBsum | ||||||||
| |||||||||
- L-lizin + O2 5-aminopentanamid + CO2 +H2O
Ovaj enzim je flavoprotein (FAD). On takođe deluje na druge diamino kiseline.
Reference uredi
- ↑ Nakazawa, T., Hori, K. and Hayaishi, O. (1972). „Studies on monooxygenases. V. Manifestation of amino acid oxidase activity by L-lysine monooxygenase”. J. Biol. Chem. 247: 3439-3444. PMID 4624115.
- ↑ Takeda, H. and Hayaishi, O. (1966). „Crystalline L-lysine oxygenase”. J. Biol. Chem. 241: 2733-2736. PMID 5911646.
- ↑ Takeda, H., Yamamoto, S., Kojima, Y. and Hayaishi, O. (1969). „Studies on monooxygenases. I. General properties of crystalline L-lysine monooxygenase”. J. Biol. Chem. 244: 2935-2941. PMID 5772467.
Literatura uredi
- Nicholas C. Price, Lewis Stevens (1999). Fundamentals of Enzymology: The Cell and Molecular Biology of Catalytic Proteins (Third izd.). USA: Oxford University Press. ISBN 019850229X.
- Eric J. Toone (2006). Advances in Enzymology and Related Areas of Molecular Biology, Protein Evolution (Volume 75 izd.). Wiley-Interscience. ISBN 0471205036.
- Branden C, Tooze J.. Introduction to Protein Structure. New York, NY: Garland Publishing. ISBN: 0-8153-2305-0.
- Irwin H. Segel. Enzyme Kinetics: Behavior and Analysis of Rapid Equilibrium and Steady-State Enzyme Systems (Book 44 izd.). Wiley Classics Library. ISBN 0471303097.
- Robert A. Copeland (2013). Evaluation of Enzyme Inhibitors in Drug Discovery: A Guide for Medicinal Chemists and Pharmacologists (2nd izd.). Wiley-Interscience. ISBN 111848813X.
- Gerhard Michal, Dietmar Schomburg (2012). Biochemical Pathways: An Atlas of Biochemistry and Molecular Biology (2nd izd.). Wiley. ISBN 0470146842.