Leuciltransferaza
Leuciltransferaza (EC 2.3.2.6, leucil, fenilalanin-tRNK-protein transferaza, leucil-fenilalanin-transfer ribonukleat-proteinska aminoaciltransferaza, leucil-fenilalanin-transfer ribonukleat-proteinska transferaza) je enzim sa sistematskim imenom L-leucil-tRNK:protein leuciltransferaza.[1][2][3] Ovaj enzim katalizuje sledeću hemijsku reakciju
| Leuciltransferaza | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| Identifikatori | |||||||||
| EC broj | 2.3.2.6 | ||||||||
| CAS broj | 37257-22-0 | ||||||||
| IntEnz | IntEnz view | ||||||||
| BRENDA | BRENDA entry | ||||||||
| ExPASy | NiceZyme view | ||||||||
| KEGG | KEGG entry | ||||||||
| MetaCyc | metabolic pathway | ||||||||
| PRIAM | profile | ||||||||
| PDB | RCSB PDB PDBe PDBj PDBsum | ||||||||
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- L-leucil-tRNK + protein tRNK + L-leucil-protein
Ova enzim takođe prenosi fenilalanilne grupe.
Reference uredi
- ↑ Leibowitz, M.J. and Soffer, R.L. (1969). „A soluble enzyme from Escherichia coli which catalyzes the transfer of leucine and phenylalanine from tRNA to acceptor proteins”. Biochem. Biophys. Res. Commun. 36: 47-53. PMID 4894363.
- ↑ Leibowitz, M.J. and Soffer, R.L. (1970). „Enzymatic modification of proteins. 3. Purification and properties of a leucyl, phenylalanyl transfer ribonucleic acid protein transferase from Escherichia coli”. J. Biol. Chem. 245: 2066-2073. PMID 4909560.
- ↑ Soffer, R.L. (1973). „Peptide acceptors in the leucine, phenylalanine transfer reaction”. J. Biol. Chem. 248: 8424-8428. PMID 4587124.
Literatura uredi
- Nicholas C. Price, Lewis Stevens (1999). Fundamentals of Enzymology: The Cell and Molecular Biology of Catalytic Proteins (Third izd.). USA: Oxford University Press. ISBN 019850229X.
- Eric J. Toone (2006). Advances in Enzymology and Related Areas of Molecular Biology, Protein Evolution (Volume 75 izd.). Wiley-Interscience. ISBN 0471205036.
- Branden C, Tooze J.. Introduction to Protein Structure. New York, NY: Garland Publishing. ISBN: 0-8153-2305-0.
- Irwin H. Segel. Enzyme Kinetics: Behavior and Analysis of Rapid Equilibrium and Steady-State Enzyme Systems (Book 44 izd.). Wiley Classics Library. ISBN 0471303097.
- Robert A. Copeland (2013). Evaluation of Enzyme Inhibitors in Drug Discovery: A Guide for Medicinal Chemists and Pharmacologists (2nd izd.). Wiley-Interscience. ISBN 111848813X.
- Gerhard Michal, Dietmar Schomburg (2012). Biochemical Pathways: An Atlas of Biochemistry and Molecular Biology (2nd izd.). Wiley. ISBN 0470146842.