Laktotriaozilkeramid beta-1,4-galaktoziltransferaza
Laktotriaozilkeramid beta-1,4-galaktoziltransferaza (EC 2.4.1.275, beta4Gal-T4, UDP-galaktoza:N-acetil-beta-D-glukozaminil-(1->3)-beta-D-galaktozil-(1->4)-beta-D-glukozil-(1<->1)-keramid beta-1,4-galaktoziltransferaza) je enzim sa sistematskim imenom UDP-alfa-D-galaktoza:N-acetil-beta-D-glukozaminil-(1->3)-beta-D-galaktozil-(1->4)-beta-D-glukozil-(1<->1)-keramid 4-beta-D-galaktoziltransferaza.[1] Ovaj enzim katalizuje sledeću hemijsku reakciju
| Laktotriaozilkeramid beta-1,4-galaktoziltransferaza | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| Identifikatori | |||||||||
| EC broj | 2.4.1.275 | ||||||||
| IntEnz | IntEnz view | ||||||||
| BRENDA | BRENDA entry | ||||||||
| ExPASy | NiceZyme view | ||||||||
| KEGG | KEGG entry | ||||||||
| MetaCyc | metabolic pathway | ||||||||
| PRIAM | profile | ||||||||
| PDB | RCSB PDB PDBe PDBj PDBsum | ||||||||
| |||||||||
- UDP-alfa-D-galaktoza + N-acetil-beta-D-glukozaminil-(1->3)-beta-D-galaktozil-(1->4)-beta-D-glukozil-(1<->1)-keramid UDP + beta-D-galaktozil-(1->4)-N-acetil-beta-D-galaktozaminil-(1->3)-beta-D-galaktozil-(1->4)-beta-D-glukozil-(1<->1)-keramid
Reference uredi
- ↑ Schwientek, T., Almeida, R., Levery, S.B., Holmes, E.H., Bennett, E. and Clausen, H. (1998). „Cloning of a novel member of the UDP-galactose:β-N-acetylglucosamine β1,4-galactosyltransferase family, β4Gal-T4, involved in glycosphingolipid biosynthesis”. J. Biol. Chem. 273: 29331-29340. PMID 9792633.
Literatura uredi
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- Eric J. Toone (2006). Advances in Enzymology and Related Areas of Molecular Biology, Protein Evolution (Volume 75 izd.). Wiley-Interscience. ISBN 0471205036.
- Branden C, Tooze J.. Introduction to Protein Structure. New York, NY: Garland Publishing. ISBN: 0-8153-2305-0.
- Irwin H. Segel. Enzyme Kinetics: Behavior and Analysis of Rapid Equilibrium and Steady-State Enzyme Systems (Book 44 izd.). Wiley Classics Library. ISBN 0471303097.
- Robert A. Copeland (2013). Evaluation of Enzyme Inhibitors in Drug Discovery: A Guide for Medicinal Chemists and Pharmacologists (2nd izd.). Wiley-Interscience. ISBN 111848813X.
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