L-687,384

L-687,384
(IUPAC) ime
	1'-benzylspiro[2,3-dihydro-1H-naphthalene-4,4'-piperidine]
Klinički podaci
Identifikatori
CAS broj	95417-67-7
ATC kod	nije dodeljen
PubChem	125328
Hemijski podaci
Formula	C21H25N
Mol. masa	291.429 g/mol
SMILES	eMolekuli & PubHem
InChI
	InChI=1S/C21H25N/c1-2-7-18(8-3-1)17-22-15-13-21(14-16-22)12-6-10-19-9-4-5-11-20(19)21/h1-5,7-9,11H,6,10,12-17H2 ; Key: MLDCBJPLHBPJET-UHFFFAOYSA-N
Farmakoinformacioni podaci
Trudnoća	?
Pravni status

L-687,384 je agonist sigma receptora. On je selektivan za σ₁ tip.^[3] On je isto tako NMDA antagonist.^[4]

Reference uredi

↑ Li Q, Cheng T, Wang Y, Bryant SH (2010). „PubChem as a public resource for drug discovery.”. Drug Discov Today 15 (23-24): 1052-7. DOI:10.1016/j.drudis.2010.10.003. PMID 20970519. edit
↑ Evan E. Bolton, Yanli Wang, Paul A. Thiessen, Stephen H. Bryant (2008). „Chapter 12 PubChem: Integrated Platform of Small Molecules and Biological Activities”. Annual Reports in Computational Chemistry 4: 217-241. DOI:10.1016/S1574-1400(08)00012-1.
↑ Bergeron R, Debonnel G (February 1997). „Effects of low and high doses of selective sigma ligands: further evidence suggesting the existence of different subtypes of sigma receptors”. Psychopharmacology 129 (3): 215–24. PMID 9084059.
↑ McLarnon J, Sawyer D, Church J (June 1994). „The actions of L-687,384, a sigma receptor ligand, on NMDA-induced currents in cultured rat hippocampal pyramidal neurons”. Neuroscience Letters 174 (2): 181–4. PMID 7526288.

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