Klostripain
Klostripain (EC 3.4.22.8, klostridiopeptidaza B, Clostridium histolyticum proteinaza B, alfa-klostridipain, klostridiopeptidaza) je enzim.[1][2][3] Ovaj enzim katalizuje sledeću hemijsku reakciju
| Klostripain | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| Identifikatori | |||||||||
| EC broj | 3.4.22.8 | ||||||||
| CAS broj | 9028-00-6 | ||||||||
| IntEnz | IntEnz view | ||||||||
| BRENDA | BRENDA entry | ||||||||
| ExPASy | NiceZyme view | ||||||||
| KEGG | KEGG entry | ||||||||
| MetaCyc | metabolic pathway | ||||||||
| PRIAM | profile | ||||||||
| PDB | RCSB PDB PDBe PDBj PDBsum | ||||||||
| |||||||||
- Preferentno razlaganje: Arg-, uklučujući Arg-Pro, ali ne i Lys-
Ovaj enzim je izolovan iz bakterije Clostridium histolyticum.
Reference uredi
- ↑ Mitchell, W.M. (1977). „Cleavage at arginine residues by clostripain”. Methods Enzymol. 47: 165-170. PMID 927173.
- ↑ Gilles, A.-M., Imhoff, J.-M. and Keil, B. (1979). „α-Clostripain. Chemical characterization, activity, and thiol content of the highly active form of clostripain”. J. Biol. Chem. 254: 1462-1468. PMID 762145.
- ↑ Gilles, A.-M., Lecroisey, A. and Keil, B. (1984). „Primary structure of α-clostripain light chain”. Eur. J. Biochem. 145: 469-476. PMID 6391922.
Literatura uredi
- Nicholas C. Price, Lewis Stevens (1999). Fundamentals of Enzymology: The Cell and Molecular Biology of Catalytic Proteins (Third izd.). USA: Oxford University Press. ISBN 019850229X.
- Eric J. Toone (2006). Advances in Enzymology and Related Areas of Molecular Biology, Protein Evolution (Volume 75 izd.). Wiley-Interscience. ISBN 0471205036.
- Branden C, Tooze J.. Introduction to Protein Structure. New York, NY: Garland Publishing. ISBN: 0-8153-2305-0.
- Irwin H. Segel. Enzyme Kinetics: Behavior and Analysis of Rapid Equilibrium and Steady-State Enzyme Systems (Book 44 izd.). Wiley Classics Library. ISBN 0471303097.
- Robert A. Copeland (2013). Evaluation of Enzyme Inhibitors in Drug Discovery: A Guide for Medicinal Chemists and Pharmacologists (2nd izd.). Wiley-Interscience. ISBN 111848813X.
- Gerhard Michal, Dietmar Schomburg (2012). Biochemical Pathways: An Atlas of Biochemistry and Molecular Biology (2nd izd.). Wiley. ISBN 0470146842.