Klostridijalna aminopeptidaza
Klostridijalna aminopeptidaza (EC 3.4.11.13, Clostridium histolyticum aminopeptidaza) je enzim sa sistematskim imenom '.[1][2][3] Ovaj enzim katalizuje sledeću hemijsku reakciju
| Klostridijalna aminopeptidaza | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| Identifikatori | |||||||||
| EC broj | 3.4.11.13 | ||||||||
| CAS broj | 59680-69-2 | ||||||||
| IntEnz | IntEnz view | ||||||||
| BRENDA | BRENDA entry | ||||||||
| ExPASy | NiceZyme view | ||||||||
| KEGG | KEGG entry | ||||||||
| MetaCyc | metabolic pathway | ||||||||
| PRIAM | profile | ||||||||
| PDB | RCSB PDB PDBe PDBj PDBsum | ||||||||
| |||||||||
- Odvajanje N-terminalne aminokiseline, uključujući prolin i hidroksiprolin. Ne dolazi do odvajanja Xaa-Pro-
Ovaj enzim izlučuje Clostridium histolyticum. Za njegov rad je neophodan Mn2+ ili Co2+.
Reference uredi
- ↑ Kessler, E. and Yaron, A. (1973). „A novel aminopeptidase from Clostridium histolyticum”. Biochem. Biophys. Res. Commun. 50: 405-412. PMID 4631895.
- ↑ Kessler, E. and Yaron, A. (1976). „An extracellular aminopeptidase from Clostridium histolyticum”. Eur. J. Biochem. 63: 271-287. PMID 4318.
- ↑ Kessler, E. and Yaron, A. (1976). „Extracellular aminopeptidase from Clostridium histolyticum”. Methods Enzymol. 45: 544-552. PMID 13266.
Literatura uredi
- Nicholas C. Price, Lewis Stevens (1999). Fundamentals of Enzymology: The Cell and Molecular Biology of Catalytic Proteins (Third izd.). USA: Oxford University Press. ISBN 019850229X.
- Eric J. Toone (2006). Advances in Enzymology and Related Areas of Molecular Biology, Protein Evolution (Volume 75 izd.). Wiley-Interscience. ISBN 0471205036.
- Branden C, Tooze J.. Introduction to Protein Structure. New York, NY: Garland Publishing. ISBN: 0-8153-2305-0.
- Irwin H. Segel. Enzyme Kinetics: Behavior and Analysis of Rapid Equilibrium and Steady-State Enzyme Systems (Book 44 izd.). Wiley Classics Library. ISBN 0471303097.
- Robert A. Copeland (2013). Evaluation of Enzyme Inhibitors in Drug Discovery: A Guide for Medicinal Chemists and Pharmacologists (2nd izd.). Wiley-Interscience. ISBN 111848813X.
- Gerhard Michal, Dietmar Schomburg (2012). Biochemical Pathways: An Atlas of Biochemistry and Molecular Biology (2nd izd.). Wiley. ISBN 0470146842.