Kinureninaza
Kinureninaza (EC 3.7.1.3) je enzim sa sistematskim imenom L-kinurenin hidrolaza.[1][2][3][4] Ovaj enzim katalizuje sledeću hemijsku reakciju
| Kinureninaza | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| |||||||||
| Kinureninaza dimer, Human | |||||||||
| Identifikatori | |||||||||
| EC broj | 3.7.1.3 | ||||||||
| CAS broj | 9024-78-6 | ||||||||
| IntEnz | IntEnz view | ||||||||
| BRENDA | BRENDA entry | ||||||||
| ExPASy | NiceZyme view | ||||||||
| KEGG | KEGG entry | ||||||||
| MetaCyc | metabolic pathway | ||||||||
| PRIAM | profile | ||||||||
| PDB | RCSB PDB PDBe PDBj PDBsum | ||||||||
| |||||||||
- L-kinurenin + H2O antranilat + L-alanin
Ovaj enzim je piridoksal-fosfatni protein.
Reference uredi
- ↑ Jakoby, W.B. and Bonner, D.M. (1953). „Kynureninase from Neurospora: purification and properties”. J. Biol. Chem. 205: 699-707. PMID 13129248.
- ↑ Jakoby, W.B. and Bonner, D.M. (1953). „Kynureninase from Neurospora: interactions of enzyme with substrates, coenzyme and amines”. J. Biol. Chem. 205: 709-715. PMID 13129249.
- ↑ Knox, W.E. (1953). „The relation of liver kynureninase to tryptophan metabolism in pyridoxine deficiency”. Biochem. J. 53: 379-385. PMID 13032082.
- ↑ Wiss, O. and Weber, F. (1956). „Die Reindarstellung der Kynureninase”. Hoppe-Seyler's Z. Physiol. Chem. 304: 232-240.
Literatura uredi
- Nicholas C. Price, Lewis Stevens (1999). Fundamentals of Enzymology: The Cell and Molecular Biology of Catalytic Proteins (Third izd.). USA: Oxford University Press. ISBN 019850229X.
- Eric J. Toone (2006). Advances in Enzymology and Related Areas of Molecular Biology, Protein Evolution (Volume 75 izd.). Wiley-Interscience. ISBN 0471205036.
- Branden C, Tooze J.. Introduction to Protein Structure. New York, NY: Garland Publishing. ISBN: 0-8153-2305-0.
- Irwin H. Segel. Enzyme Kinetics: Behavior and Analysis of Rapid Equilibrium and Steady-State Enzyme Systems (Book 44 izd.). Wiley Classics Library. ISBN 0471303097.
- Robert A. Copeland (2013). Evaluation of Enzyme Inhibitors in Drug Discovery: A Guide for Medicinal Chemists and Pharmacologists (2nd izd.). Wiley-Interscience. ISBN 111848813X.
- Gerhard Michal, Dietmar Schomburg (2012). Biochemical Pathways: An Atlas of Biochemistry and Molecular Biology (2nd izd.). Wiley. ISBN 0470146842.