Hloramfenikol O-acetiltransferaza
Hloramfenikol O-acetiltransferaza (EC 2.3.1.28, hloramfenikol acetiltransferaza, hloramfenikol acetilaza, hloramfenikol transacetilaza, CAT I, CAT II, CAT III) je enzim sa sistematskim imenom acetil-KoA:hloramfenikol 3-O-acetiltransferaza.[1][2] Ovaj enzim katalizuje sledeću hemijsku reakciju
| Hloramfenikol O-acetiltransferaza | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| |||||||||
| Identifikatori | |||||||||
| EC broj | 2.3.1.28 | ||||||||
| CAS broj | 2608021 | ||||||||
| IntEnz | IntEnz view | ||||||||
| BRENDA | BRENDA entry | ||||||||
| ExPASy | NiceZyme view | ||||||||
| KEGG | KEGG entry | ||||||||
| MetaCyc | metabolic pathway | ||||||||
| PRIAM | profile | ||||||||
| PDB | RCSB PDB PDBe PDBj PDBsum | ||||||||
| |||||||||
- acetil-KoA + hloramfenikol KoA + hloramfenikol 3-acetat
Reference uredi
- ↑ Shaw, W.V. (1967). „The enzymatic acetylation of chloramphenicol by extracts of R factor-resistant Escherichia coli”. J. Biol. Chem. 242: 687-693. PMID 5335032.
- ↑ Shaw, W.V. and Brodsky, R.F. (1968). „Characterization of chloramphenicol acetyltransferase from chloramphenicol-resistant Staphylococcus aureus'”. J. Bacteriol. 95: 28-36. PMID 4965980.
Literatura uredi
- Nicholas C. Price, Lewis Stevens (1999). Fundamentals of Enzymology: The Cell and Molecular Biology of Catalytic Proteins (Third izd.). USA: Oxford University Press. ISBN 019850229X.
- Eric J. Toone (2006). Advances in Enzymology and Related Areas of Molecular Biology, Protein Evolution (Volume 75 izd.). Wiley-Interscience. ISBN 0471205036.
- Branden C, Tooze J.. Introduction to Protein Structure. New York, NY: Garland Publishing. ISBN: 0-8153-2305-0.
- Irwin H. Segel. Enzyme Kinetics: Behavior and Analysis of Rapid Equilibrium and Steady-State Enzyme Systems (Book 44 izd.). Wiley Classics Library. ISBN 0471303097.
- Robert A. Copeland (2013). Evaluation of Enzyme Inhibitors in Drug Discovery: A Guide for Medicinal Chemists and Pharmacologists (2nd izd.). Wiley-Interscience. ISBN 111848813X.
- Gerhard Michal, Dietmar Schomburg (2012). Biochemical Pathways: An Atlas of Biochemistry and Molecular Biology (2nd izd.). Wiley. ISBN 0470146842.