Hitozanaza
Hitozanaza (EC 3.2.1.132, Chitosanase) je enzim sa sistematskim imenom hitozan N-acetilglukozaminohidrolaza.[1][2][3][4] Ovaj enzim katalizuje sledeću hemijsku reakciju
| Hitozanaza | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| Identifikatori | |||||||||
| EC broj | 3.2.1.132 | ||||||||
| CAS broj | 51570-20-8 | ||||||||
| IntEnz | IntEnz view | ||||||||
| BRENDA | BRENDA entry | ||||||||
| ExPASy | NiceZyme view | ||||||||
| KEGG | KEGG entry | ||||||||
| MetaCyc | metabolic pathway | ||||||||
| PRIAM | profile | ||||||||
| PDB | RCSB PDB PDBe PDBj PDBsum | ||||||||
| |||||||||
- Endohidroliza beta-(1->4)-veza između D-glukozaminskih ostataka u parcijalno acetilisanom hitozanu
Pozant je čitav spektar hitozanaza.
Reference uredi
- ↑ Fenton, D.M. and Eveleigh, D.E. (1981). „Purification and mode of action of a chitosanase from Penicillium islandicum”. J. Gen. Microbiol. 126: 151-165.
- ↑ Saito, J.-I., Kita, A., Higuchi, Y., Nagata, Y., Ando, A. and Miki, K. (1999). „Crystal structure of chitosanase from Bacillus circulans MH-K1 at 1.6-Å resolution and its substrate recognition mechanism”. J. Biol. Chem. 274: 30818-30825. PMID 10521473.
- ↑ Izume, M., Nagae, S., Kawagishi, H., Mitsutomi, M. and Ohtakara, A. (1992). „Action pattern of Bacillus sp. No. 7-M chitosanase on partially N-acetylated chitosan”. Biosci. Biotechnol. Biochem. 56: 448-453. PMID 1368330.
- ↑ Marcotte, E.M., Monzingo, A.F., Ernst, S.R., Brzezinski, R. and Robertus, J.D. (1996). „X-ray structure of an anti-fungal chitosanase from Streptomyces N174”. Nat. Struct. Biol. 3: 155-162. PMID 8564542.
Literatura uredi
- Nicholas C. Price, Lewis Stevens (1999). Fundamentals of Enzymology: The Cell and Molecular Biology of Catalytic Proteins (Third izd.). USA: Oxford University Press. ISBN 019850229X.
- Eric J. Toone (2006). Advances in Enzymology and Related Areas of Molecular Biology, Protein Evolution (Volume 75 izd.). Wiley-Interscience. ISBN 0471205036.
- Branden C, Tooze J.. Introduction to Protein Structure. New York, NY: Garland Publishing. ISBN: 0-8153-2305-0.
- Irwin H. Segel. Enzyme Kinetics: Behavior and Analysis of Rapid Equilibrium and Steady-State Enzyme Systems (Book 44 izd.). Wiley Classics Library. ISBN 0471303097.
- Robert A. Copeland (2013). Evaluation of Enzyme Inhibitors in Drug Discovery: A Guide for Medicinal Chemists and Pharmacologists (2nd izd.). Wiley-Interscience. ISBN 111848813X.
- Gerhard Michal, Dietmar Schomburg (2012). Biochemical Pathways: An Atlas of Biochemistry and Molecular Biology (2nd izd.). Wiley. ISBN 0470146842.