HIV-1 retropepsin
HIV-1 retropepsin (EC 3.4.23.16, proteaza ljudskog virusa imunodeficijencije tipa 1, gag proteaza, HIV aspartilna proteaza, HIV proteinaza, retroproteinaza, HIV-1 proteaza, HIV-2 proteaza) je enzim.[1][2] Ovaj enzim katalizuje sledeću hemijsku reakciju
| HIV-1 retropepsin | |||||||||
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| Identifikatori | |||||||||
| EC broj | 3.4.23.16 | ||||||||
| CAS broj | 144114-21-6 | ||||||||
| IntEnz | IntEnz view | ||||||||
| BRENDA | BRENDA entry | ||||||||
| ExPASy | NiceZyme view | ||||||||
| KEGG | KEGG entry | ||||||||
| MetaCyc | metabolic pathway | ||||||||
| PRIAM | profile | ||||||||
| PDB | RCSB PDB PDBe PDBj PDBsum | ||||||||
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- Specifično dejstvo na hidrofobne P1 ostatke, do P1' može da bude varijabilno i često je Pro
Ovaj enzim kodira ljudski virus imunodeficijencije tipa 1
Reference uredi
Literatura uredi
- Nicholas C. Price, Lewis Stevens (1999). Fundamentals of Enzymology: The Cell and Molecular Biology of Catalytic Proteins (Third izd.). USA: Oxford University Press. ISBN 019850229X.
- Eric J. Toone (2006). Advances in Enzymology and Related Areas of Molecular Biology, Protein Evolution (Volume 75 izd.). Wiley-Interscience. ISBN 0471205036.
- Branden C, Tooze J.. Introduction to Protein Structure. New York, NY: Garland Publishing. ISBN: 0-8153-2305-0.
- Irwin H. Segel. Enzyme Kinetics: Behavior and Analysis of Rapid Equilibrium and Steady-State Enzyme Systems (Book 44 izd.). Wiley Classics Library. ISBN 0471303097.
- Robert A. Copeland (2013). Evaluation of Enzyme Inhibitors in Drug Discovery: A Guide for Medicinal Chemists and Pharmacologists (2nd izd.). Wiley-Interscience. ISBN 111848813X.
- Gerhard Michal, Dietmar Schomburg (2012). Biochemical Pathways: An Atlas of Biochemistry and Molecular Biology (2nd izd.). Wiley. ISBN 0470146842.
- Dunn, B.M. (1998). „Human immunodeficiency virus 1 retropepsin”. u: Barrett, A.J., Rawlings, N.D. and Woessner, J.F.. Handbook of Proteolytic Enzymes. London: Academic Press. str. 919-928.