Glutation oksidaza
Glutation oksidaza (EC 1.8.3.3, glutationska oksidaza) je enzim sa sistematskim imenom glutation:kiseonik oksidoreduktaza.[1] Ovaj enzim katalizuje sledeću hemijsku reakciju:
| Glutation oksidaza | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| Identifikatori | |||||||||
| EC broj | 1.8.3.3 | ||||||||
| CAS broj | 55467-56-6 | ||||||||
| IntEnz | IntEnz view | ||||||||
| BRENDA | BRENDA entry | ||||||||
| ExPASy | NiceZyme view | ||||||||
| KEGG | KEGG entry | ||||||||
| MetaCyc | metabolic pathway | ||||||||
| PRIAM | profile | ||||||||
| PDB | RCSB PDB PDBe PDBj PDBsum | ||||||||
| |||||||||
- 2 glutation + O2 glutation disulfid +H2O2
Ovaj enzim je flavoprotein (FAD). On takođe deluje, mada sporo, na L-cistein i nekoliko drugih tiola.
Reference uredi
- ↑ Kusakabe, H., Kuninaka, A. and Yoshino, H. (1982). „Purification and properties of a new enzyme, glutathione oxidase from Penicillium sp.K-6-5”. Agric. Biol. Chem. 46: 2057-2067.
Literatura uredi
- Nicholas C. Price, Lewis Stevens (1999). Fundamentals of Enzymology: The Cell and Molecular Biology of Catalytic Proteins (Third izd.). USA: Oxford University Press. ISBN 019850229X.
- Eric J. Toone (2006). Advances in Enzymology and Related Areas of Molecular Biology, Protein Evolution (Volume 75 izd.). Wiley-Interscience. ISBN 0471205036.
- Branden C, Tooze J.. Introduction to Protein Structure. New York, NY: Garland Publishing. ISBN: 0-8153-2305-0.
- Irwin H. Segel. Enzyme Kinetics: Behavior and Analysis of Rapid Equilibrium and Steady-State Enzyme Systems (Book 44 izd.). Wiley Classics Library. ISBN 0471303097.
- Robert A. Copeland (2013). Evaluation of Enzyme Inhibitors in Drug Discovery: A Guide for Medicinal Chemists and Pharmacologists (2nd izd.). Wiley-Interscience. ISBN 111848813X.
- Gerhard Michal, Dietmar Schomburg (2012). Biochemical Pathways: An Atlas of Biochemistry and Molecular Biology (2nd izd.). Wiley. ISBN 0470146842.