Glicerol dehidrogenaza
Glicerol dehidrogenaza (EC 1.1.1.6, glicerolna dehidrogenaza, glicerin dehidrogenaza, NAD+-vezani glicerol dehidrogenaza) je enzim sa sistematskim imenom glicerol:NAD+ 2-oksidoreduktaza.[1][2][3] Ovaj enzim katalizuje sledeću hemijsku reakciju
| Glicerol dehidrogenaza | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| Identifikatori | |||||||||
| EC broj | 1.1.1.6 | ||||||||
| CAS broj | 9028-14-2 | ||||||||
| IntEnz | IntEnz view | ||||||||
| BRENDA | BRENDA entry | ||||||||
| ExPASy | NiceZyme view | ||||||||
| KEGG | KEGG entry | ||||||||
| MetaCyc | metabolic pathway | ||||||||
| PRIAM | profile | ||||||||
| PDB | RCSB PDB PDBe PDBj PDBsum | ||||||||
| |||||||||
- glicerol + NAD+ gliceron + NADH + H+
Ovaj enzim takođe deluje na propan-1,2-diol.
Reference uredi
- ↑ Asnis, R.E. and Brodie, A.F. (1953). „A glycerol dehydrogenase from Escherichia coli”. J. Biol. Chem. 203: 153-159. PMID 13069498.
- ↑ Burton, R.M. and Kaplan, N.O. (1953). „A DPN specific glycerol dehydrogenase from Aerobacter aerogenes”. J. Am. Chem. Soc. 75: 1005-1007.
- ↑ Lin, E.C.C. and Magasanik, B. (1960). „The activation of glycerol dehydrogenase from Aerobacter aerogenes by monovalent cations”. J. Biol. Chem. 235: 1820-1823. PMID 14417009.
Literatura uredi
- Nicholas C. Price, Lewis Stevens (1999). Fundamentals of Enzymology: The Cell and Molecular Biology of Catalytic Proteins (Third izd.). USA: Oxford University Press. ISBN 019850229X.
- Eric J. Toone (2006). Advances in Enzymology and Related Areas of Molecular Biology, Protein Evolution (Volume 75 izd.). Wiley-Interscience. ISBN 0471205036.
- Branden C, Tooze J.. Introduction to Protein Structure. New York, NY: Garland Publishing. ISBN: 0-8153-2305-0.
- Irwin H. Segel. Enzyme Kinetics: Behavior and Analysis of Rapid Equilibrium and Steady-State Enzyme Systems (Book 44 izd.). Wiley Classics Library. ISBN 0471303097.
- Robert A. Copeland (2013). Evaluation of Enzyme Inhibitors in Drug Discovery: A Guide for Medicinal Chemists and Pharmacologists (2nd izd.). Wiley-Interscience. ISBN 111848813X.
- Gerhard Michal, Dietmar Schomburg (2012). Biochemical Pathways: An Atlas of Biochemistry and Molecular Biology (2nd izd.). Wiley. ISBN 0470146842.