G-glutamilciklotransferaza
G-glutamilciklotransferaza (EC 2.3.2.4, gama-glutamil-aminokiselinska ciklotransferaza, gama-L-glutamilciklotransferaza, L-glutaminska ciklaza, (5-L-glutamil)-L-aminokiselinska 5-glutamiltransferaza (ciklizacija)) je enzim sa sistematskim imenom (gama-L-glutamil)-L-amino-kiselina gama-glutamiltransferaza (ciklizacija).[1][2] Ovaj enzim katalizuje sledeću hemijsku reakciju
| G-glutamilciklotransferaza | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| Identifikatori | |||||||||
| EC broj | 2.3.2.4 | ||||||||
| CAS broj | 9045-44-7 | ||||||||
| IntEnz | IntEnz view | ||||||||
| BRENDA | BRENDA entry | ||||||||
| ExPASy | NiceZyme view | ||||||||
| KEGG | KEGG entry | ||||||||
| MetaCyc | metabolic pathway | ||||||||
| PRIAM | profile | ||||||||
| PDB | RCSB PDB PDBe PDBj PDBsum | ||||||||
| |||||||||
- (gama-L-glutamil)-L-aminokiselina 5-oksoprolin + L-aminokiselina
Ovaj enzim deluje na derivate L-glutamata, L-2-aminobutanoata, L-alanina i glicina.
Reference uredi
- ↑ Bodnaryk, R.P. and McGirr, L. (1973). „Purification, properties and function of a unique γ-glutamyl cyclotransferase from the housefly, Musca domestica L”. Biochim. Biophys. Acta 315: 352-362.
- ↑ Orlowski, M., Richman, P.G. and Meister, A. (1969). „Isolation and properties of γ-L-glutamylcyclotransferase from human brain”. Biochemistry 8: 1048-1055. PMID 5781001.
Literatura uredi
- Nicholas C. Price, Lewis Stevens (1999). Fundamentals of Enzymology: The Cell and Molecular Biology of Catalytic Proteins (Third izd.). USA: Oxford University Press. ISBN 019850229X.
- Eric J. Toone (2006). Advances in Enzymology and Related Areas of Molecular Biology, Protein Evolution (Volume 75 izd.). Wiley-Interscience. ISBN 0471205036.
- Branden C, Tooze J.. Introduction to Protein Structure. New York, NY: Garland Publishing. ISBN: 0-8153-2305-0.
- Irwin H. Segel. Enzyme Kinetics: Behavior and Analysis of Rapid Equilibrium and Steady-State Enzyme Systems (Book 44 izd.). Wiley Classics Library. ISBN 0471303097.
- Robert A. Copeland (2013). Evaluation of Enzyme Inhibitors in Drug Discovery: A Guide for Medicinal Chemists and Pharmacologists (2nd izd.). Wiley-Interscience. ISBN 111848813X.
- Gerhard Michal, Dietmar Schomburg (2012). Biochemical Pathways: An Atlas of Biochemistry and Molecular Biology (2nd izd.). Wiley. ISBN 0470146842.