Fosforibozilaminoimidazolkarboksamid formiltransferaza
Fosforibozilaminoimidazolkarboksamid formiltransferaza (EC 2.1.2.3, 5-amino-4-imidazolkarboksamid ribonukleotidna transformilaza, AICAR transformilaza, 10-formiltetrahidrofolat:5'-fosforibozil-5-amino-4-imidazolkarboksamidna formiltransferaza, 5'-fosforibozil-5-amino-4-imidazolkarboksamidna formiltransferaza, 5-amino-1-ribozil-4-imidazolekarboksamid 5'-fosfatna transformilaza, 5-amino-4-imidazolkarboksamid ribotidna transformilaza, AICAR formiltransferaza, aminoimidazolkarboksamid ribonukleotidna transformilaza) je enzim sa sistematskim imenom 10-formiltetrahidrofolat:5'-fosforibozil-5-amino-4-imidazol-karboksamid N-formiltransferaza.[1] Ovaj enzim katalizuje sledeću hemijsku reakciju
| Fosforibozilaminoimidazolkarboksamid formiltransferaza | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| Identifikatori | |||||||||
| EC broj | 2.1.2.3 | ||||||||
| CAS broj | 2604975 | ||||||||
| IntEnz | IntEnz view | ||||||||
| BRENDA | BRENDA entry | ||||||||
| ExPASy | NiceZyme view | ||||||||
| KEGG | KEGG entry | ||||||||
| MetaCyc | metabolic pathway | ||||||||
| PRIAM | profile | ||||||||
| PDB | RCSB PDB PDBe PDBj PDBsum | ||||||||
| |||||||||
- 10-formiltetrahidrofolat + 5-amino-1-(5-fosfo-D-ribozil)imidazol-4-karboksamid tetrahidrofolat + 5-formamido-1-(5-fosfo-D-ribozil)imidazol-4-karboksamid
Reference uredi
- ↑ Hartman, S.C. and Buchanan, J.M. (1959). „Biosynthesis of the purines. XXVI. The identification of the formyl donors of the transformylation reaction”. J. Biol. Chem. 234: 1812-1816. PMID 13672969.
Literatura uredi
- Nicholas C. Price, Lewis Stevens (1999). Fundamentals of Enzymology: The Cell and Molecular Biology of Catalytic Proteins (Third izd.). USA: Oxford University Press. ISBN 019850229X.
- Eric J. Toone (2006). Advances in Enzymology and Related Areas of Molecular Biology, Protein Evolution (Volume 75 izd.). Wiley-Interscience. ISBN 0471205036.
- Branden C, Tooze J.. Introduction to Protein Structure. New York, NY: Garland Publishing. ISBN: 0-8153-2305-0.
- Irwin H. Segel. Enzyme Kinetics: Behavior and Analysis of Rapid Equilibrium and Steady-State Enzyme Systems (Book 44 izd.). Wiley Classics Library. ISBN 0471303097.
- Robert A. Copeland (2013). Evaluation of Enzyme Inhibitors in Drug Discovery: A Guide for Medicinal Chemists and Pharmacologists (2nd izd.). Wiley-Interscience. ISBN 111848813X.
- Gerhard Michal, Dietmar Schomburg (2012). Biochemical Pathways: An Atlas of Biochemistry and Molecular Biology (2nd izd.). Wiley. ISBN 0470146842.