Enoil-(acil-nosilac-protein) reduktaza (NADH)
Enoil-(acil-nosilac-protein) reduktaza (NADH) (EC 1.3.1.9, enoil-(acil nosilac protein) reduktaza, enoil-ACP reduktaza, NADH-enoil acil nosilac protein reduktaza, NADH-specifična enoil-ACP reduktaza, acil-(acil-nosilac-protein):NAD+ oksidoreduktaza) je enzim sa sistematskim imenom acil-(acil-nosilac protein):NAD+ oksidoreduktaza.[1][2] Ovaj enzim katalizuje sledeću hemijsku reakciju
| Enoil-(acil-nosilac-protein) reduktaza (NADH) | |||||||||
|---|---|---|---|---|---|---|---|---|---|
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| Enoil-(acil-nosilac-protein) reduktaza (NADH) tetramer, Mycobacterium tuberculosis | |||||||||
| Identifikatori | |||||||||
| EC broj | 1.3.1.9 | ||||||||
| CAS broj | 37251-08-4 | ||||||||
| IntEnz | IntEnz view | ||||||||
| BRENDA | BRENDA entry | ||||||||
| ExPASy | NiceZyme view | ||||||||
| KEGG | KEGG entry | ||||||||
| MetaCyc | metabolic pathway | ||||||||
| PRIAM | profile | ||||||||
| PDB | RCSB PDB PDBe PDBj PDBsum | ||||||||
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- acil-[acil-nosilac protein] + NAD+ trans-2,3-dehidroacil-[acil-nosilac protein] + NADH + H+
Ovaj enzim katalizuje redukciju enoil-acil-[acil-nosilac-protein] derivata sa ugljeničnim lancom dužine od 4 do 16.
Reference uredi
- ↑ Shimakata, T. and Stumpf, P.K. (1982). „Purification and characterizations of β-ketoacyl-[acyl-carrier-protein] reductase, β-hydroxyacyl-[acylcarrier-protein] dehydrase, and enoyl-[acyl-carrier-protein] reductase from Spinacia oleracea leaves”. Arch. Biochem. Biophys. 218: 77-91. PMID 6756317.
- ↑ Weeks, G. and Wakil, S.J. (1968). „Studies on the mechanism of fatty acid synthesis. 18. Preparation and general properties of the enoyl acyl carrier protein reductases from Escherichia coli”. J. Biol. Chem. 243: 1180-1189. PMID 4384650.
Literatura uredi
- Nicholas C. Price, Lewis Stevens (1999). Fundamentals of Enzymology: The Cell and Molecular Biology of Catalytic Proteins (Third izd.). USA: Oxford University Press. ISBN 019850229X.
- Eric J. Toone (2006). Advances in Enzymology and Related Areas of Molecular Biology, Protein Evolution (Volume 75 izd.). Wiley-Interscience. ISBN 0471205036.
- Branden C, Tooze J.. Introduction to Protein Structure. New York, NY: Garland Publishing. ISBN: 0-8153-2305-0.
- Irwin H. Segel. Enzyme Kinetics: Behavior and Analysis of Rapid Equilibrium and Steady-State Enzyme Systems (Book 44 izd.). Wiley Classics Library. ISBN 0471303097.
- Robert A. Copeland (2013). Evaluation of Enzyme Inhibitors in Drug Discovery: A Guide for Medicinal Chemists and Pharmacologists (2nd izd.). Wiley-Interscience. ISBN 111848813X.
- Gerhard Michal, Dietmar Schomburg (2012). Biochemical Pathways: An Atlas of Biochemistry and Molecular Biology (2nd izd.). Wiley. ISBN 0470146842.