Dihidrobenzofenantridin oksidaza
Dihidrobenzofenantridin oksidaza (EC 1.5.3.12, dihidrobenzofenantridinska oksidaza) je enzim sa sistematskim imenom dihidrobenzofenantridin:kiseonik oksidoreduktaza.[1][2] Ovaj enzim katalizuje sledeću hemijsku reakciju:
| Dihidrobenzofenantridin oksidaza | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| Identifikatori | |||||||||
| EC broj | 1.5.3.12 | ||||||||
| CAS broj | 114051-83-1 | ||||||||
| IntEnz | IntEnz view | ||||||||
| BRENDA | BRENDA entry | ||||||||
| ExPASy | NiceZyme view | ||||||||
| KEGG | KEGG entry | ||||||||
| MetaCyc | metabolic pathway | ||||||||
| PRIAM | profile | ||||||||
| PDB | RCSB PDB PDBe PDBj PDBsum | ||||||||
| |||||||||
- (1) dihidrosanguinarin + O2 sanguinarin + H2O2
- (2) dihidrohelirubin + O2 helirubin + H2O2
- (3) dihidromakarpin + O2 makarpin + H2O2
Ovaj enzim je prisutan kod viših biljki koje formirmaju oksidovane forme benzofenantridinskih alkaloida.
Reference uredi
- ↑ Schumacher, H.-M. and Zenk, M.H. (1988). „Partial purification and characterization of dihydrobenzophenanthridine oxidase from Eschscholtzia tenuifolia cell suspension cultures”. Plant Cell Reports 7: 43-46.
- ↑ Arakawa, H., Clark, W.G. (1992). „, Psenak. M. and Coscia, C.J. Purification and characterization of dihydrobenzophenanthridine oxidase from elicited Sanguinaria canadensis cell cultures”. Arch. Biochem. Biophys. 299: 1-7. PMID 1444440.
Literatura uredi
- Nicholas C. Price, Lewis Stevens (1999). Fundamentals of Enzymology: The Cell and Molecular Biology of Catalytic Proteins (Third izd.). USA: Oxford University Press. ISBN 019850229X.
- Eric J. Toone (2006). Advances in Enzymology and Related Areas of Molecular Biology, Protein Evolution (Volume 75 izd.). Wiley-Interscience. ISBN 0471205036.
- Branden C, Tooze J.. Introduction to Protein Structure. New York, NY: Garland Publishing. ISBN: 0-8153-2305-0.
- Irwin H. Segel. Enzyme Kinetics: Behavior and Analysis of Rapid Equilibrium and Steady-State Enzyme Systems (Book 44 izd.). Wiley Classics Library. ISBN 0471303097.
- Robert A. Copeland (2013). Evaluation of Enzyme Inhibitors in Drug Discovery: A Guide for Medicinal Chemists and Pharmacologists (2nd izd.). Wiley-Interscience. ISBN 111848813X.
- Gerhard Michal, Dietmar Schomburg (2012). Biochemical Pathways: An Atlas of Biochemistry and Molecular Biology (2nd izd.). Wiley. ISBN 0470146842.