Decilcitrat sintaza
Decilcitrat sintaza (EC 2.3.3.2, 2-decilcitratna sintaza, (2S,3S)-2-hidroksitridekan-1,2,3-trikarboksilat oksaloacetatna lijaza (KoA-acilacija)) je enzim sa sistematskim imenom dodekanoil-KoA:oksaloacetat C-dodekanoiltransferaza (tioestarska hidroliza, formiranje 1-karboksiundecila).[1][2] Ovaj enzim katalizuje sledeću hemijsku reakciju
| Decilcitrat sintaza | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| Identifikatori | |||||||||
| EC broj | 2.3.3.2 | ||||||||
| CAS broj | 9068-72-8 | ||||||||
| IntEnz | IntEnz view | ||||||||
| BRENDA | BRENDA entry | ||||||||
| ExPASy | NiceZyme view | ||||||||
| KEGG | KEGG entry | ||||||||
| MetaCyc | metabolic pathway | ||||||||
| PRIAM | profile | ||||||||
| PDB | RCSB PDB PDBe PDBj PDBsum | ||||||||
| |||||||||
- lauroil-KoA + H2O + oksaloacetat (2S,3S)-2-hidroksitridekan-1,2,3-trikarboksilat + KoA
Reference uredi
- ↑ Maahlén, A. and Gatenbeck, S. (1968). „A metabolic variation in Penicillium spiculisporum Lehman. II. Purification and some properties of the enzyme synthesizing (-)-decylcitric acid”. Acta Chem. Scand. 22: 2617-2623. PMID 5719165.
- ↑ Maahlén, A. (1971). „Properties of 2-decylcitrate synthase from Penicillium spiculisporum Lehman”. Eur. J. Biochem. 22: 104-114. PMID 5099208.
Literatura uredi
- Nicholas C. Price, Lewis Stevens (1999). Fundamentals of Enzymology: The Cell and Molecular Biology of Catalytic Proteins (Third izd.). USA: Oxford University Press. ISBN 019850229X.
- Eric J. Toone (2006). Advances in Enzymology and Related Areas of Molecular Biology, Protein Evolution (Volume 75 izd.). Wiley-Interscience. ISBN 0471205036.
- Branden C, Tooze J.. Introduction to Protein Structure. New York, NY: Garland Publishing. ISBN: 0-8153-2305-0.
- Irwin H. Segel. Enzyme Kinetics: Behavior and Analysis of Rapid Equilibrium and Steady-State Enzyme Systems (Book 44 izd.). Wiley Classics Library. ISBN 0471303097.
- Robert A. Copeland (2013). Evaluation of Enzyme Inhibitors in Drug Discovery: A Guide for Medicinal Chemists and Pharmacologists (2nd izd.). Wiley-Interscience. ISBN 111848813X.
- Gerhard Michal, Dietmar Schomburg (2012). Biochemical Pathways: An Atlas of Biochemistry and Molecular Biology (2nd izd.). Wiley. ISBN 0470146842.