Diaminobutirat—2-oksoglutarat transaminaza
(Preusmjereno sa stranice DABA aminotransferaza)
Diaminobutirat—2-oksoglutarat transaminaza (EC 2.6.1.76, L-2,4-diaminobutirat:2-ketoglutarat 4-aminotransferaza, 2,4-diaminobutirat 4-aminotransferaza, diaminobutirat aminotransferaza, DABA aminotransferaza, DAB aminotransferaza, EctB, diaminibutirna kiselina aminotransferaza, L-2,4-diaminobutirat:2-oksoglutarat 4-aminotransferaza) je enzim sa sistematskim imenom L-2,4-diaminobutanoat:2-oksoglutarat 4-aminotransferaza.[1][2][3][4][5][6] Ovaj enzim katalizuje sledeću hemijsku reakciju
| Diaminobutirat—2-oksoglutarat transaminaza | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| Identifikatori | |||||||||
| EC broj | 2.6.1.76 | ||||||||
| CAS broj | 196622-96-5 | ||||||||
| IntEnz | IntEnz view | ||||||||
| BRENDA | BRENDA entry | ||||||||
| ExPASy | NiceZyme view | ||||||||
| KEGG | KEGG entry | ||||||||
| MetaCyc | metabolic pathway | ||||||||
| PRIAM | profile | ||||||||
| PDB | RCSB PDB PDBe PDBj PDBsum | ||||||||
| |||||||||
- L-2,4-diaminobutanoat + 2-oksoglutarat L-aspartat 4-semialdehid + L-glutamat
Za dejtvo ovog piridoksal-fosfatnog proteina je neophodan kalijum.
Reference uredi
- ↑ Ikai, H. and Yamamoto, S. (1997). „Identification and analysis of a gene encoding L-2,4-diaminobutyrate:2-ketoglutarate 4-aminotransferase involved in the 1,3-diaminopropane production pathway in Acinetobacter baumannii”. J. Bacteriol. 179: 5118-5125. PMID 9260954.
- ↑ Ikai, H. and Yamamoto, S. (1998). „Two genes involved in the 1,3-diaminopropane production pathway in Haemophilus influenzae”. Biol. Pharm. Bull. 21: 170-173. PMID 9514614.
- ↑ Peters, P., Galinski, E.A. and Truper, H.G. (1990). „The biosynthesis of ectoine”. FEMS Microbiol. Lett. 71: 157-162.
- ↑ Ono, H., Sawada, K., Khunajakr, N., Tao, T., Yamamoto, M., Hiramoto, M., Shinmyo, A., Takano, M. and Murooka, Y. (1999). „Characterization of biosynthetic enzymes for ectoine as a compatible solute in a moderately halophilic eubacterium, Halomonas elongata”. J. Bacteriol. 181: 91-99. PMID 9864317.
- ↑ Kuhlmann, A.U. and Bremer, E. (2002). „Osmotically regulated synthesis of the compatible solute ectoine in Bacillus pasteurii and related Bacillus spp”. Appl. Environ. Microbiol. 68: 772-783. PMID 11823218.
- ↑ Louis, P. and Galinski, E.A. (1997). „Characterization of genes for the biosynthesis of the compatible solute ectoine from Marinococcus halophilus and osmoregulated expression in Escherichia coli”. Microbiology 143: 1141-1149. PMID 9141677.
Literatura uredi
- Nicholas C. Price, Lewis Stevens (1999). Fundamentals of Enzymology: The Cell and Molecular Biology of Catalytic Proteins (Third izd.). USA: Oxford University Press. ISBN 019850229X.
- Eric J. Toone (2006). Advances in Enzymology and Related Areas of Molecular Biology, Protein Evolution (Volume 75 izd.). Wiley-Interscience. ISBN 0471205036.
- Branden C, Tooze J.. Introduction to Protein Structure. New York, NY: Garland Publishing. ISBN: 0-8153-2305-0.
- Irwin H. Segel. Enzyme Kinetics: Behavior and Analysis of Rapid Equilibrium and Steady-State Enzyme Systems (Book 44 izd.). Wiley Classics Library. ISBN 0471303097.
- Robert A. Copeland (2013). Evaluation of Enzyme Inhibitors in Drug Discovery: A Guide for Medicinal Chemists and Pharmacologists (2nd izd.). Wiley-Interscience. ISBN 111848813X.
- Gerhard Michal, Dietmar Schomburg (2012). Biochemical Pathways: An Atlas of Biochemistry and Molecular Biology (2nd izd.). Wiley. ISBN 0470146842.