D-laktat dehidrogenaza
D-laktat dehidrogenaza (EC 1.1.1.28, D-laktatna dehidrogenaza, mlečna kiselina dehidrogenaza, mlečna kiselina dehidrogenaza, D-specifična mlečna dehidrogenaza, D-(-)-laktat dehidrogenaza (NAD+), D-mlečna kiselina dehidrogenaza, D-mlečna dehidrogenaza) je enzim sa sistematskim imenom (R)-laktat:NAD+ oksidoreduktaza.[1] Ovaj enzim katalizuje sledeću hemijsku reakciju
| D-laktat dehidrogenaza | |||||||||
|---|---|---|---|---|---|---|---|---|---|
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| Tetramer laktat dehidrogenaze M (LDH5) (čovjek) | |||||||||
| Identifikatori | |||||||||
| EC broj | 1.1.1.28 | ||||||||
| CAS broj | 9028-36-8 | ||||||||
| IntEnz | IntEnz view | ||||||||
| BRENDA | BRENDA entry | ||||||||
| ExPASy | NiceZyme view | ||||||||
| KEGG | KEGG entry | ||||||||
| MetaCyc | metabolic pathway | ||||||||
| PRIAM | profile | ||||||||
| PDB | RCSB PDB PDBe PDBj PDBsum | ||||||||
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- (R)-laktat + NAD+ piruvat + NADH + H+
Reference uredi
- ↑ Dennis, D. and Kaplan, N.O. (1960). „D and L-lactic acid dehydrogenase in Lactobacillus plantarum”. J. Biol. Chem. 235: 810-818. PMID 13815938.
Literatura uredi
- Nicholas C. Price, Lewis Stevens (1999). Fundamentals of Enzymology: The Cell and Molecular Biology of Catalytic Proteins (Third izd.). USA: Oxford University Press. ISBN 019850229X.
- Eric J. Toone (2006). Advances in Enzymology and Related Areas of Molecular Biology, Protein Evolution (Volume 75 izd.). Wiley-Interscience. ISBN 0471205036.
- Branden C, Tooze J.. Introduction to Protein Structure. New York, NY: Garland Publishing. ISBN: 0-8153-2305-0.
- Irwin H. Segel. Enzyme Kinetics: Behavior and Analysis of Rapid Equilibrium and Steady-State Enzyme Systems (Book 44 izd.). Wiley Classics Library. ISBN 0471303097.
- Robert A. Copeland (2013). Evaluation of Enzyme Inhibitors in Drug Discovery: A Guide for Medicinal Chemists and Pharmacologists (2nd izd.). Wiley-Interscience. ISBN 111848813X.
- Gerhard Michal, Dietmar Schomburg (2012). Biochemical Pathways: An Atlas of Biochemistry and Molecular Biology (2nd izd.). Wiley. ISBN 0470146842.