Citohrom-b5 reduktaza
Citohrom-b5 reduktaza (EC 1.6.2.2, citohromna b5 reduktaza, dihidronikotinamid adenin dinukleotid-citohrom b5 reduktaza, redukovani nikotinamid adenindinukleotid-citohrom b5 reduktaza, NADH-fericitohrom b5 oksidoreduktaza, NADH-citohrom b5 reduktaza, NADH 5alfa-reduktaza, NADH-citohrom-b5 reduktaza) je enzim sa sistematskim imenom NADH:fericitohrom-b5 oksidoreduktaza.[1][2][3] Ovaj enzim katalizuje sledeću hemijsku reakciju
| Citohrom-b5 reduktaza | |||||||||
|---|---|---|---|---|---|---|---|---|---|
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| Identifikatori | |||||||||
| EC broj | 1.6.2.2 | ||||||||
| CAS broj | 9032-25-1 | ||||||||
| IntEnz | IntEnz view | ||||||||
| BRENDA | BRENDA entry | ||||||||
| ExPASy | NiceZyme view | ||||||||
| KEGG | KEGG entry | ||||||||
| MetaCyc | metabolic pathway | ||||||||
| PRIAM | profile | ||||||||
| PDB | RCSB PDB PDBe PDBj PDBsum | ||||||||
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- NADH + 2 fericitohrom b5 NAD+ + H+ + 2 ferocitohrom b5
Ovaj enzim je flavoprotein (FAD).
Reference uredi
- ↑ Mahler, H.R., Raw, I., Molinari, R. and do Amaral, D.F. (1958). „Studies of electron transport enzymes. II. Isolation and some properties of a cytochrome-specific reduced diphosphopyridine nucleotide dehydrogenase from pig liver”. J. Biol. Chem. 233: 230-239. PMID 13563476.
- ↑ Strittmatter, P. (1963). „Microsomal cytochrome b5 and cytochrome b5 reductase”. u: Boyer, P.D., Lardy, H. and Myrbäck, K.. The Enzymes. 8 (2nd izd.). New York: Academic Press. str. 113-145.
- ↑ Strittmatter, P. and Velick, S.F. (1957). „The purification and properties of microsomal cytochrome reductase”. J. Biol. Chem. 228: 785-799. PMID 13475360.
Literatura uredi
- Nicholas C. Price, Lewis Stevens (1999). Fundamentals of Enzymology: The Cell and Molecular Biology of Catalytic Proteins (Third izd.). USA: Oxford University Press. ISBN 019850229X.
- Eric J. Toone (2006). Advances in Enzymology and Related Areas of Molecular Biology, Protein Evolution (Volume 75 izd.). Wiley-Interscience. ISBN 0471205036.
- Branden C, Tooze J.. Introduction to Protein Structure. New York, NY: Garland Publishing. ISBN: 0-8153-2305-0.
- Irwin H. Segel. Enzyme Kinetics: Behavior and Analysis of Rapid Equilibrium and Steady-State Enzyme Systems (Book 44 izd.). Wiley Classics Library. ISBN 0471303097.
- Robert A. Copeland (2013). Evaluation of Enzyme Inhibitors in Drug Discovery: A Guide for Medicinal Chemists and Pharmacologists (2nd izd.). Wiley-Interscience. ISBN 111848813X.
- Gerhard Michal, Dietmar Schomburg (2012). Biochemical Pathways: An Atlas of Biochemistry and Molecular Biology (2nd izd.). Wiley. ISBN 0470146842.