Botropasin
Botropasin (EC 3.4.24.49, Bothrops jararaca venomna metaloproteinaza) je enzim.[1] Ovaj enzim katalizuje sledeću hemijsku reakciju
| Botropasin | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| Identifikatori | |||||||||
| EC broj | 3.4.24.49 | ||||||||
| CAS broj | 84788-89-6 | ||||||||
| IntEnz | IntEnz view | ||||||||
| BRENDA | BRENDA entry | ||||||||
| ExPASy | NiceZyme view | ||||||||
| KEGG | KEGG entry | ||||||||
| MetaCyc | metabolic pathway | ||||||||
| PRIAM | profile | ||||||||
| PDB | RCSB PDB PDBe PDBj PDBsum | ||||||||
| |||||||||
- Razlaganje His5-Leu, His10-Leu, Ala14-Leu, Tyr16-Leu i Phe24-Phe u insulinskom B lancu
Ova kazeinolitička endopeptidaza je prisutna u venumu zmije Bothrops jararaca.
Reference uredi
- ↑ Mandelbaum, F.J., Reichel, A.P. and Assakura, M.T. (1982). „Isolation and characterization of a proteolytic enzyme from the venom of the snake Bothrops jararaca (jararaca)”. Toxicon 20: 955-972. PMID 6819660.
Literatura uredi
- Nicholas C. Price, Lewis Stevens (1999). Fundamentals of Enzymology: The Cell and Molecular Biology of Catalytic Proteins (Third izd.). USA: Oxford University Press. ISBN 019850229X.
- Eric J. Toone (2006). Advances in Enzymology and Related Areas of Molecular Biology, Protein Evolution (Volume 75 izd.). Wiley-Interscience. ISBN 0471205036.
- Branden C, Tooze J.. Introduction to Protein Structure. New York, NY: Garland Publishing. ISBN: 0-8153-2305-0.
- Irwin H. Segel. Enzyme Kinetics: Behavior and Analysis of Rapid Equilibrium and Steady-State Enzyme Systems (Book 44 izd.). Wiley Classics Library. ISBN 0471303097.
- Robert A. Copeland (2013). Evaluation of Enzyme Inhibitors in Drug Discovery: A Guide for Medicinal Chemists and Pharmacologists (2nd izd.). Wiley-Interscience. ISBN 111848813X.
- Gerhard Michal, Dietmar Schomburg (2012). Biochemical Pathways: An Atlas of Biochemistry and Molecular Biology (2nd izd.). Wiley. ISBN 0470146842.