Biotinidaza
Biotinidaza (EC 3.5.1.12, amidohidrolaza biotinidaza) je enzim sa sistematskim imenom biotin-amid amidohidrolaza.[1][2] Ovaj enzim katalizuje sledeću hemijsku reakciju
| Biotinidaza | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| Identifikatori | |||||||||
| EC broj | 3.5.1.12 | ||||||||
| CAS broj | 9025-15-4 | ||||||||
| IntEnz | IntEnz view | ||||||||
| BRENDA | BRENDA entry | ||||||||
| ExPASy | NiceZyme view | ||||||||
| KEGG | KEGG entry | ||||||||
| MetaCyc | metabolic pathway | ||||||||
| PRIAM | profile | ||||||||
| PDB | RCSB PDB PDBe PDBj PDBsum | ||||||||
| |||||||||
- biotinski amid + H2O biotin + NH3
Ovaj enzim takođe deluje na biotinske estre.
Reference uredi
- ↑ Knappe, J., Brümer, W. and Biederbick, K. (1963). „Reinigung und Eigenschaften der Biotinidase aus Schweinenieren und Lactobacillus casei”. Biochem. Z. 338: 599-613. PMID 14087327.
- ↑ Thoma, R.W. and Peterson, W.H. (1954). „The enzymatic degradation of soluble bound biotin”. J. Biol. Chem. 210: 569-579. PMID 13211594.
Literatura uredi
- Nicholas C. Price, Lewis Stevens (1999). Fundamentals of Enzymology: The Cell and Molecular Biology of Catalytic Proteins (Third izd.). USA: Oxford University Press. ISBN 019850229X.
- Eric J. Toone (2006). Advances in Enzymology and Related Areas of Molecular Biology, Protein Evolution (Volume 75 izd.). Wiley-Interscience. ISBN 0471205036.
- Branden C, Tooze J.. Introduction to Protein Structure. New York, NY: Garland Publishing. ISBN: 0-8153-2305-0.
- Irwin H. Segel. Enzyme Kinetics: Behavior and Analysis of Rapid Equilibrium and Steady-State Enzyme Systems (Book 44 izd.). Wiley Classics Library. ISBN 0471303097.
- Robert A. Copeland (2013). Evaluation of Enzyme Inhibitors in Drug Discovery: A Guide for Medicinal Chemists and Pharmacologists (2nd izd.). Wiley-Interscience. ISBN 111848813X.
- Gerhard Michal, Dietmar Schomburg (2012). Biochemical Pathways: An Atlas of Biochemistry and Molecular Biology (2nd izd.). Wiley. ISBN 0470146842.