Arginin 2-monooksigenaza
Arginin 2-monooksigenaza (EC 1.13.12.1, argininska monooksigenaza, argininska dekarboksilaza, argininska oksigenaza (dekarboksilacija), argininska dekarboksi-oksidaza) je enzim sa sistematskim imenom L-arginin:kiseonik 2-oksidoreduktaza (dekarboksilacija).[1][2][3] Ovaj enzim katalizuje sledeću hemijsku reakciju
| Arginin 2-monooksigenaza | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| Identifikatori | |||||||||
| EC broj | 1.13.12.1 | ||||||||
| CAS broj | 9027-36-5 | ||||||||
| IntEnz | IntEnz view | ||||||||
| BRENDA | BRENDA entry | ||||||||
| ExPASy | NiceZyme view | ||||||||
| KEGG | KEGG entry | ||||||||
| MetaCyc | metabolic pathway | ||||||||
| PRIAM | profile | ||||||||
| PDB | RCSB PDB PDBe PDBj PDBsum | ||||||||
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- L-arginin + O2 4-guanidinobutanamid + CO2 + H2O
Ovaj enzim je flavoprotein. On takođe deluje na kanavanin i homoarginin.
Reference uredi
- ↑ Olomucki, A., Pho, D.B., Lebar, R., Delcambe, L. and Thoai, N.V. (1968). „Arginine oxygénase décarboxylante. V. Purification et nature flavinique”. Biochim. Biophys. Acta 151: 353-366. PMID 4295160.
- ↑ Thoai, N.V. and Olomucki, A. (1962). „Arginine décarboxy-oxydase. I. Caractères et nature de l’enzyme”. Biochim. Biophys. Acta 59: 533-544.
- ↑ Thoai, N.V. and Olomucki, A. (1962). „Arginine décarboxy-oxydase. II. Oxydation de la canavanine et de l’homoarginine en β-guanidopropionamide et en δ-guanidovaleramide”. Biochim. Biophys. Acta 59: 545-552.
Literatura uredi
- Nicholas C. Price, Lewis Stevens (1999). Fundamentals of Enzymology: The Cell and Molecular Biology of Catalytic Proteins (Third izd.). USA: Oxford University Press. ISBN 019850229X.
- Eric J. Toone (2006). Advances in Enzymology and Related Areas of Molecular Biology, Protein Evolution (Volume 75 izd.). Wiley-Interscience. ISBN 0471205036.
- Branden C, Tooze J.. Introduction to Protein Structure. New York, NY: Garland Publishing. ISBN: 0-8153-2305-0.
- Irwin H. Segel. Enzyme Kinetics: Behavior and Analysis of Rapid Equilibrium and Steady-State Enzyme Systems (Book 44 izd.). Wiley Classics Library. ISBN 0471303097.
- Robert A. Copeland (2013). Evaluation of Enzyme Inhibitors in Drug Discovery: A Guide for Medicinal Chemists and Pharmacologists (2nd izd.). Wiley-Interscience. ISBN 111848813X.
- Gerhard Michal, Dietmar Schomburg (2012). Biochemical Pathways: An Atlas of Biochemistry and Molecular Biology (2nd izd.). Wiley. ISBN 0470146842.