Apiozna 1-reduktaza
U enzimologiji, apioza 1-reduktaza (EC 1.1.1.114) je enzim koji katalizuje sledeću hemijsku reakciju
| Apiozna 1-reduktaza | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| Identifikatori | |||||||||
| EC broj | 1.1.1.114 | ||||||||
| CAS broj | 37250-45-6 | ||||||||
| IntEnz | IntEnz view | ||||||||
| BRENDA | BRENDA entry | ||||||||
| ExPASy | NiceZyme view | ||||||||
| KEGG | KEGG entry | ||||||||
| MetaCyc | metabolic pathway | ||||||||
| PRIAM | profile | ||||||||
| PDB | RCSB PDB PDBe PDBj PDBsum | ||||||||
| Ontologija gena | AmiGO / EGO | ||||||||
| |||||||||
- D-apiitol + NAD+ D-apioza + NADH + H+
Dva supstrata ovog enzima su D-apiitol i NAD+, dok su njegova 3 proizvoda D-apioza, NADH, i H+.[1][2]
Ovaj enzim pripada familiji oksidoreduktaza, specifično onih koje deluju na CH-OH grupi donora sa NAD+ ili NADP+ akceptorom. Sistematsko ime ove enzimske klase je D-apiitol:NAD+ 1-oksidoreduktaza. Druga imena u čestoj upotrebi su D-apiozna reduktaza, i D-apiitolna reduktaza.
Reference uredi
- ↑ Hanna R, Picken M and Mendicino J (1973). „Purification of a specific D-apiitol dehydrogenase from a Micrococcus isolated from the surface of germinating parsley seeds”. Biochim. Biophys. Acta 315: 259-271.
- ↑ Neal DL, Kindel PK (1970). „D-apiose reductase from Aerobacter aerogenes”. J. Bacteriol. 101 (3): 910-5. PMC 250409. PMID 4314545.
Literatura uredi
- Nicholas C. Price, Lewis Stevens (1999). Fundamentals of Enzymology: The Cell and Molecular Biology of Catalytic Proteins (Third izd.). USA: Oxford University Press. ISBN 019850229X.
- Eric J. Toone (2006). Advances in Enzymology and Related Areas of Molecular Biology, Protein Evolution (Volume 75 izd.). Wiley-Interscience. ISBN 0471205036.
- Branden C, Tooze J.. Introduction to Protein Structure. New York, NY: Garland Publishing. ISBN: 0-8153-2305-0.
- Irwin H. Segel. Enzyme Kinetics: Behavior and Analysis of Rapid Equilibrium and Steady-State Enzyme Systems (Book 44 izd.). Wiley Classics Library. ISBN 0471303097.
- Robert A. Copeland (2013). Evaluation of Enzyme Inhibitors in Drug Discovery: A Guide for Medicinal Chemists and Pharmacologists (2nd izd.). Wiley-Interscience. ISBN 111848813X.
- Gerhard Michal, Dietmar Schomburg (2012). Biochemical Pathways: An Atlas of Biochemistry and Molecular Biology (2nd izd.). Wiley. ISBN 0470146842.