Alinska lijaza
Alinska lijaza (EC 4.4.1.4, alinaza, cistein sulfoksidna lijaza, alkilcistein sulfoksidna lijaza, S-alkilcistein sulfoksidna lijaza, L-cistein sulfoksidna lijaza, S-alkil-L-cistein sulfoksidna lijaza, alin alkil-sulfenat-lijaza) je enzim sa sistematskim imenom S-alkil-L-cistein S-oksid alkil-sulfenat-lijaza (formira 2-aminoakrilat).[1][2][3] Ovaj enzim katalizuje sledeću hemijsku reakciju
| Alinska lijaza | |||||||||
|---|---|---|---|---|---|---|---|---|---|
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| Identifikatori | |||||||||
| EC broj | 4.4.1.4 | ||||||||
| CAS broj | 9031-77-0 | ||||||||
| IntEnz | IntEnz view | ||||||||
| BRENDA | BRENDA entry | ||||||||
| ExPASy | NiceZyme view | ||||||||
| KEGG | KEGG entry | ||||||||
| MetaCyc | metabolic pathway | ||||||||
| PRIAM | profile | ||||||||
| PDB | RCSB PDB PDBe PDBj PDBsum | ||||||||
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- S-alkil-L-cistein S-oksid alkil sulfenat + 2-aminoakrilat
Ovaj enzim je piridoksal-fosfatni protein.
Reference uredi
- ↑ Durbin, R.D. and Uchytil, T.F. (1971). „Purification and properties of alliin lyase from the fungus Penicillium corymbiferum”. Biochim. Biophys. Acta 235: 518-520.
- ↑ Goryachenkova, E.V. (1952). „[Enzyme in garlic which forms allycine (allyinase), a protein with phosphopyridoxal.]”. Dokl. Akad. Nauk. S.S.S.R. 87: 457-460.
- ↑ Jacobsen, J.V., Yamaguchi, M., Howard, F.D. and Bernhard, R.A. (1968). „Product inhibition of the cysteine sulfoxide lyase of Tulbaghia violacea”. Arch. Biochem. Biophys. 127: 252-258.
Literatura uredi
- Nicholas C. Price, Lewis Stevens (1999). Fundamentals of Enzymology: The Cell and Molecular Biology of Catalytic Proteins (Third izd.). USA: Oxford University Press. ISBN 019850229X.
- Eric J. Toone (2006). Advances in Enzymology and Related Areas of Molecular Biology, Protein Evolution (Volume 75 izd.). Wiley-Interscience. ISBN 0471205036.
- Branden C, Tooze J.. Introduction to Protein Structure. New York, NY: Garland Publishing. ISBN: 0-8153-2305-0.
- Irwin H. Segel. Enzyme Kinetics: Behavior and Analysis of Rapid Equilibrium and Steady-State Enzyme Systems (Book 44 izd.). Wiley Classics Library. ISBN 0471303097.
- Robert A. Copeland (2013). Evaluation of Enzyme Inhibitors in Drug Discovery: A Guide for Medicinal Chemists and Pharmacologists (2nd izd.). Wiley-Interscience. ISBN 111848813X.
- Gerhard Michal, Dietmar Schomburg (2012). Biochemical Pathways: An Atlas of Biochemistry and Molecular Biology (2nd izd.). Wiley. ISBN 0470146842.