Alanin-tRNK ligaza
Alanin-tRNK ligaza (EC 6.1.1.7, alanil-tRNK sintetaza, alanil-transferna ribonukleatna sintetaza, alanil-transfer RNK sintetaza, alanil-transferna ribonukleinsko kiselinska sintetaza, alanin-transfer RNK ligaza, alanin transfer RNK sintetaza, alanin tRNK sintetaza, alanin translaza, alanil-transfer ribonukleat sintaza, AlaRS, Ala-tRNK sintetaza) je enzim sa sistematskim imenom L-alanin:tRNKAla ligaza (formira AMP).[1][2] Ovaj enzim katalizuje sledeću hemijsku reakciju
| Alanin-tRNK ligaza | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| Identifikatori | |||||||||
| EC broj | 6.1.1.7 | ||||||||
| CAS broj | 9031-71-4 | ||||||||
| IntEnz | IntEnz view | ||||||||
| BRENDA | BRENDA entry | ||||||||
| ExPASy | NiceZyme view | ||||||||
| KEGG | KEGG entry | ||||||||
| MetaCyc | metabolic pathway | ||||||||
| PRIAM | profile | ||||||||
| PDB | RCSB PDB PDBe PDBj PDBsum | ||||||||
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Reference uredi
- ↑ Holley, R.W. and Goldstein, J. (1959). „An alanine-dependent, ribonuclease-inhibited conversion of adenosine 5′-phosphate to adenosine triphosphate”. J. Biol. Chem. 234: 1765-1768. PMID 13672960.
- ↑ Webster, G.C. (1961). „Isolation of an alanine-activating enzyme from pig liver”. Biochim. Biophys. Acta 49: 141-152. PMID 13783653.
Literatura uredi
- Nicholas C. Price, Lewis Stevens (1999). Fundamentals of Enzymology: The Cell and Molecular Biology of Catalytic Proteins (Third izd.). USA: Oxford University Press. ISBN 019850229X.
- Eric J. Toone (2006). Advances in Enzymology and Related Areas of Molecular Biology, Protein Evolution (Volume 75 izd.). Wiley-Interscience. ISBN 0471205036.
- Branden C, Tooze J.. Introduction to Protein Structure. New York, NY: Garland Publishing. ISBN: 0-8153-2305-0.
- Irwin H. Segel. Enzyme Kinetics: Behavior and Analysis of Rapid Equilibrium and Steady-State Enzyme Systems (Book 44 izd.). Wiley Classics Library. ISBN 0471303097.
- Robert A. Copeland (2013). Evaluation of Enzyme Inhibitors in Drug Discovery: A Guide for Medicinal Chemists and Pharmacologists (2nd izd.). Wiley-Interscience. ISBN 111848813X.
- Gerhard Michal, Dietmar Schomburg (2012). Biochemical Pathways: An Atlas of Biochemistry and Molecular Biology (2nd izd.). Wiley. ISBN 0470146842.