A-1,4-glukan-protein sintaza (UDP-formiranje)
A-1,4-glukan-protein sintaza (UDP-formiranje) (EC 2.4.1.112, UDP-glukoza:protein glukoziltransferaza, glikogen inicijator sintaza, UDPGlc:protein transglukozilaza, UPTG, uridin difosfoglukoza protein transglukozilaza I, proglikogen sintaza, uridin difosfoglukoza-protein 4-alfa-glukoziltransferaza, uridin difosfoglukoza-protein glukoziltransferaza, UDP-glukoza protein transglukozilaza, UDP-glukoza-protein glukoziltransferaza, uridin difosfat glukoza-protein transglukozilaza I) je enzim sa sistematskim imenom UDP-glukoza:protein 4-alfa-glukoziltransferaza.[1][2][3] Ovaj enzim katalizuje sledeću hemijsku reakciju
| A-1,4-glukan-protein sintaza (UDP-formiranje) | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| Identifikatori | |||||||||
| EC broj | 2.4.1.112 | ||||||||
| CAS broj | 152478-54-1 | ||||||||
| IntEnz | IntEnz view | ||||||||
| BRENDA | BRENDA entry | ||||||||
| ExPASy | NiceZyme view | ||||||||
| KEGG | KEGG entry | ||||||||
| MetaCyc | metabolic pathway | ||||||||
| PRIAM | profile | ||||||||
| PDB | RCSB PDB PDBe PDBj PDBsum | ||||||||
| |||||||||
- UDP-glukoza + protein UDP + alfa-D-glukozil-protein
Ova enzim gradi alfa-1,4-glukanske lance kovalentno vezane za proteina, te deluje kao inicijator glikogenske sinteze.
Reference uredi
- ↑ Barengo, R. and Krisman, C.R. (1978). „Initiation of glycogen biosynthesis in Escherichia coli. Studies of the properties of the enzymes involved”. Biochim. Biophys. Acta 540: 190-196. PMID 418819.
- ↑ Butler, N.A., Lee, E.Y.C. and Whelan, W.J. (1977). „A protein-bound glycogen component of rat liver”. Carbohydr. Res. 55: 73-82. PMID 861979.
- ↑ Krisman, C.R. and Barengo, R. (1975). „A precursor of glycogen biosynthesis: α-1,4-glucan-protein”. Eur. J. Biochem. 52: 117-123. PMID 809265.
Literatura uredi
- Nicholas C. Price, Lewis Stevens (1999). Fundamentals of Enzymology: The Cell and Molecular Biology of Catalytic Proteins (Third izd.). USA: Oxford University Press. ISBN 019850229X.
- Eric J. Toone (2006). Advances in Enzymology and Related Areas of Molecular Biology, Protein Evolution (Volume 75 izd.). Wiley-Interscience. ISBN 0471205036.
- Branden C, Tooze J.. Introduction to Protein Structure. New York, NY: Garland Publishing. ISBN: 0-8153-2305-0.
- Irwin H. Segel. Enzyme Kinetics: Behavior and Analysis of Rapid Equilibrium and Steady-State Enzyme Systems (Book 44 izd.). Wiley Classics Library. ISBN 0471303097.
- Robert A. Copeland (2013). Evaluation of Enzyme Inhibitors in Drug Discovery: A Guide for Medicinal Chemists and Pharmacologists (2nd izd.). Wiley-Interscience. ISBN 111848813X.
- Gerhard Michal, Dietmar Schomburg (2012). Biochemical Pathways: An Atlas of Biochemistry and Molecular Biology (2nd izd.). Wiley. ISBN 0470146842.