4-Aminobutirat transaminaza
4-aminobutirat transaminaza (EC 2.6.1.19, beta-alanin-oksoglutaratna transaminaza, aminobutiratna aminotransferaza, beta-alaninska aminotransferaza, beta-alanin-oksoglutaratna aminotransferaza, gama-aminobutiratna aminotransaminaza, gama-aminobutiratna transaminaza, gama-aminobutirat-alfa-ketoglutaratna aminotransferaza, gama-aminobutirat-alfa-ketoglutaratna transaminaza, gama-aminobutirat:alfa-oksoglutarat aminotransferaza, gama-aminobutirna kiselina aminotransferaza, gama-aminobutirna kiselina transaminaza, gama-aminobutirna kiselina-alfa-ketoglutarat transaminaza, gama-aminobutirna kiselina-alfa-ketoglutarna kiselina aminotransferaza, gama-aminobutirna kiselina-2-oksoglutarat transaminaza, gama-aminobutirna transaminaza, 4-aminobutirat aminotransferaza, 4-aminobutirat-2-ketoglutarat aminotransferaza, 4-aminobutirat-2-oksoglutarat aminotransferaza, 4-aminobutirat-2-oksoglutarat transaminaza, 4-aminobutirna kiselina 2-ketoglutarinska kiselina aminotransferaza, 4-aminobutirna kiselina aminotransferaza, aminobutirat transaminaza, GABA aminotransferaza, GABA transaminaza, GABA transferaza, GABA-alfa-ketoglutarat aminotransferaza, GABA-alfa-ketoglutarat transaminaza, GABA-alfa-ketoglutaric kiselina transaminaza, GABA-alfa-oksoglutarat aminotransferaza, GABA-2-oksoglutarat aminotransferaza, GABA-2-oksoglutarat transaminaza, GABA-oksoglutarat aminotransferaza, GABA-oksoglutarat transaminaza, glutamat-sukcinski semialdehid transaminaza, GabT) je enzim sa sistematskim imenom 4-aminobutanoat:2-oksoglutarat aminotransferaza.[1][2][3][4] Ovaj enzim katalizuje sledeću hemijsku reakciju
| 4-aminobutirat transaminaza | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| |||||||||
| Identifikatori | |||||||||
| EC broj | 2.6.1.19 | ||||||||
| CAS broj | 9037-67-6 | ||||||||
| IntEnz | IntEnz view | ||||||||
| BRENDA | BRENDA entry | ||||||||
| ExPASy | NiceZyme view | ||||||||
| KEGG | KEGG entry | ||||||||
| MetaCyc | metabolic pathway | ||||||||
| PRIAM | profile | ||||||||
| PDB | RCSB PDB PDBe PDBj PDBsum | ||||||||
| |||||||||
- 4-aminobutanoat + 2-oksoglutarat sukcinat semialdehid + L-glutamat
Ovaj enzim je piridoksal-fosfatni protein.
Reference uredi
- ↑ Scott, E.M. and Jakoby, W.B. (1959). „Soluble γ-aminobutyric-glutamic transaminase from Pseudomonas fluorescens”. J. Biol. Chem. 234: 932-936. PMID 13654294.
- ↑ Aurich, H. (1961). „Über die β-Alanin-α-Ketoglutarat-Transaminase aus Neurospora crassa”. Hoppe-Seyler's Z. Physiol. Chem. 326: 25-33. PMID 13863304.
- ↑ Schausboe, A., Wu, J.-Y. and Roberts, E. (1973). „Purification and characterization of the 4-aminobutyrate-2-ketoglutarate transaminase from mouse brain”. Biochemistry 12: 2868-2873. PMID 4719123.
- ↑ Bartsch, K., von Johnn-Marteville, A. and Schulz, A. (1990). „Molecular analysis of two genes of the Escherichia coli gab cluster: nucleotide sequence of the glutamate:succinic semialdehyde transaminase gene (gabT) and characterization of the succinic semialdehyde dehydrogenase gene (gabD)”. J. Bacteriol. 172: 7035-7042. PMID 2254272.
Literatura uredi
- Nicholas C. Price, Lewis Stevens (1999). Fundamentals of Enzymology: The Cell and Molecular Biology of Catalytic Proteins (Third izd.). USA: Oxford University Press. ISBN 019850229X.
- Eric J. Toone (2006). Advances in Enzymology and Related Areas of Molecular Biology, Protein Evolution (Volume 75 izd.). Wiley-Interscience. ISBN 0471205036.
- Branden C, Tooze J.. Introduction to Protein Structure. New York, NY: Garland Publishing. ISBN: 0-8153-2305-0.
- Irwin H. Segel. Enzyme Kinetics: Behavior and Analysis of Rapid Equilibrium and Steady-State Enzyme Systems (Book 44 izd.). Wiley Classics Library. ISBN 0471303097.
- Robert A. Copeland (2013). Evaluation of Enzyme Inhibitors in Drug Discovery: A Guide for Medicinal Chemists and Pharmacologists (2nd izd.). Wiley-Interscience. ISBN 111848813X.
- Gerhard Michal, Dietmar Schomburg (2012). Biochemical Pathways: An Atlas of Biochemistry and Molecular Biology (2nd izd.). Wiley. ISBN 0470146842.