3-Hidroksipropionil-KoA dehidrataza
3-Hidroksipropionil-KoA dehidrataza (EC 4.2.1.116, 3-hydroxypropionyl-CoA dehydratase) je enzim sa sistematskim imenom 3-hidroksipropionil-KoA hidrolijaza.[1][2] Ovaj enzim katalizuje sledeću hemijsku reakciju
3-Hidroksipropionil-KoA dehidrataza | |||||||||
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Identifikatori | |||||||||
EC broj | 4.2.1.116 | ||||||||
IntEnz | IntEnz view | ||||||||
BRENDA | BRENDA entry | ||||||||
ExPASy | NiceZyme view | ||||||||
KEGG | KEGG entry | ||||||||
MetaCyc | metabolic pathway | ||||||||
PRIAM | profile | ||||||||
PDB | RCSB PDB PDBe PDBj PDBsum | ||||||||
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- 3-hidroksipropanoil-KoA akrilil-KoA + H2O
Ovaj enzim katalizuje jedan od koraka u 3-hidroksipropionat/4-hidroksibutiratnom ciklusu.
Reference
uredi- ↑ Berg, I.A., Kockelkorn, D., Buckel, W. and Fuchs, G. (2007). „A 3-hydroxypropionate/4-hydroxybutyrate autotrophic carbon dioxide assimilation pathway in Archaea”. Science 318: 1782-1786. PMID 18079405.
- ↑ Teufel, R., Kung, J.W., Kockelkorn, D., Alber, B.E. and Fuchs, G. (2009). „3-hydroxypropionyl-coenzyme A dehydratase and acryloyl-coenzyme A reductase, enzymes of the autotrophic 3-hydroxypropionate/4-hydroxybutyrate cycle in the Sulfolobales”. J. Bacteriol. 191: 4572-4581. PMID 19429610.
Literatura
uredi- Nicholas C. Price, Lewis Stevens (1999). Fundamentals of Enzymology: The Cell and Molecular Biology of Catalytic Proteins (Third izd.). USA: Oxford University Press. ISBN 019850229X.
- Eric J. Toone (2006). Advances in Enzymology and Related Areas of Molecular Biology, Protein Evolution (Volume 75 izd.). Wiley-Interscience. ISBN 0471205036.
- Branden C, Tooze J.. Introduction to Protein Structure. New York, NY: Garland Publishing. ISBN: 0-8153-2305-0.
- Irwin H. Segel. Enzyme Kinetics: Behavior and Analysis of Rapid Equilibrium and Steady-State Enzyme Systems (Book 44 izd.). Wiley Classics Library. ISBN 0471303097.
- Robert A. Copeland (2013). Evaluation of Enzyme Inhibitors in Drug Discovery: A Guide for Medicinal Chemists and Pharmacologists (2nd izd.). Wiley-Interscience. ISBN 111848813X.
- Gerhard Michal, Dietmar Schomburg (2012). Biochemical Pathways: An Atlas of Biochemistry and Molecular Biology (2nd izd.). Wiley. ISBN 0470146842.