2-Kumarat O-b-glukoziltransferaza
2-kumarat O-b-glukoziltransferaza (EC 2.4.1.114, uridin difosfoglukoza-o-kumarat glukoziltransferaza, UDPG:o-kumarinska kiselina O-glukoziltransferaza) je enzim sa sistematskim imenom UDP-glukoza:trans-2-hidroksicinamat O-beta-D-glukoziltransferaza.[1][2] Ovaj enzim katalizuje sledeću hemijsku reakciju
| 2-kumarat O-b-glukoziltransferaza | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| Identifikatori | |||||||||
| EC broj | 2.4.1.114 | ||||||||
| CAS broj | 73665-97-1 | ||||||||
| IntEnz | IntEnz view | ||||||||
| BRENDA | BRENDA entry | ||||||||
| ExPASy | NiceZyme view | ||||||||
| KEGG | KEGG entry | ||||||||
| MetaCyc | metabolic pathway | ||||||||
| PRIAM | profile | ||||||||
| PDB | RCSB PDB PDBe PDBj PDBsum | ||||||||
| |||||||||
- UDP-glukoza + trans-2-hidroksicinamat UDP + trans-beta-D-glukozil-2-hidroksicinamat
Kumarinat (cis-2-hidroksicinamat) ne može da deluje kao akceptor.
Reference uredi
- ↑ Kleinhofs, A., Haskins, F.A. and Gorz, H.J. (1967). „trans-o-Hydroxylcinnamic acid glucosylation in cell-free extracts of Melilotus alba”. Phytochemistry 6: 1313-1318.
- ↑ Poulton, J.E., McRee, B.E. and Conn, E.E. (1980). „Intracellular localization of two enzymes involved in coumarin biosynthesis in Melilotus alba”. Plant Physiol. 65: 171-175. PMID 16661155.
Literatura uredi
- Nicholas C. Price, Lewis Stevens (1999). Fundamentals of Enzymology: The Cell and Molecular Biology of Catalytic Proteins (Third izd.). USA: Oxford University Press. ISBN 019850229X.
- Eric J. Toone (2006). Advances in Enzymology and Related Areas of Molecular Biology, Protein Evolution (Volume 75 izd.). Wiley-Interscience. ISBN 0471205036.
- Branden C, Tooze J.. Introduction to Protein Structure. New York, NY: Garland Publishing. ISBN: 0-8153-2305-0.
- Irwin H. Segel. Enzyme Kinetics: Behavior and Analysis of Rapid Equilibrium and Steady-State Enzyme Systems (Book 44 izd.). Wiley Classics Library. ISBN 0471303097.
- Robert A. Copeland (2013). Evaluation of Enzyme Inhibitors in Drug Discovery: A Guide for Medicinal Chemists and Pharmacologists (2nd izd.). Wiley-Interscience. ISBN 111848813X.
- Gerhard Michal, Dietmar Schomburg (2012). Biochemical Pathways: An Atlas of Biochemistry and Molecular Biology (2nd izd.). Wiley. ISBN 0470146842.