(KDO)-lipid IVA 3-dezoksi-D-mano-oktulozonska kiselina transferaza
(KDO)-lipid IVA 3-dezoksi-D-mano-oktulozonska kiselina transferaza (EC 2.4.99.13, KDO transferaza, waaA (gen), kdtA (gen), Kdo transferaza, 3-dezoksi-D-mano-okt-2-ulozonska kiselina transferaza, 3-dezoksi-mano-oktulozonska kiselina transferaza) je enzim sa sistematskim imenom CMP-3-dezoksi-D-mano-okt-2-ulozonat:(KDO)-lipid IVA 3-dezoksi-D-mano-okt-2-ulozonat transferaza.[1][2] Ovaj enzim katalizuje sledeću hemijsku reakciju
| (KDO)-lipid IVA 3-dezoksi-D-mano-oktulozonska kiselina transferaza | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| Identifikatori | |||||||||
| EC broj | 2.4.99.13 | ||||||||
| IntEnz | IntEnz view | ||||||||
| BRENDA | BRENDA entry | ||||||||
| ExPASy | NiceZyme view | ||||||||
| KEGG | KEGG entry | ||||||||
| MetaCyc | metabolic pathway | ||||||||
| PRIAM | profile | ||||||||
| PDB | RCSB PDB PDBe PDBj PDBsum | ||||||||
| |||||||||
- alfa-Kdo-(2->6)-lipid IVA + CMP-alfa-Kdo alfa-Kdo-(2->4)-alfa-Kdo-(2->6)-lipid IVA + CMP
Ovaj bifunkcionalani enzim iz Escherichia coli prenosi dva 3-dezoksi-D-mano-okt-2-ulozonatna ostataka na lipid IVA (cf. EC 2.4.99.12 [(KDO)-lipid IVA 3-dezoksi-D-mano-oktulozonska kiselina transferaza]).
Reference uredi
- ↑ Belunis, C.J. and Raetz, C.R. (1992). „Biosynthesis of endotoxins. Purification and catalytic properties of 3-deoxy-D-manno-octulosonic acid transferase from Escherichia coli”. J. Biol. Chem. 267: 9988-9997. PMID 1577828.
- ↑ Lobau, S., Mamat, U., Brabetz, W. and Brade, H. (1995). „Molecular cloning, sequence analysis, and functional characterization of the lipopolysaccharide biosynthetic gene kdtA encoding 3-deoxy-α-D-manno-octulosonic acid transferase of Chlamydia pneumoniae strain TW-183”. Mol. Microbiol. 18: 391-399. PMID 8748024.
Literatura uredi
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